rps6ka3 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (123)

Nucleotides (97)

Interactants (101)

XB-GENEPAGE-480946

Gene Symbol: rps6ka3 Gene Name: ribosomal protein S6 kinase, 90kDa, polypeptide 3 Synonyms: protein kinase p90, S6 kinase II, S6KII, S6 kinase, p90, rsk, rsk2 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: mapk1(52) , rps6ka1(50) , ins(24) , cdk1(22) , mos(22) , ccnb1.2(16) , pold1(12) View All

XB-GENE-480947

XB-GENE-865425

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002936044\|PREDICTED: Xenopus (Silurana) tropicalis ribosomal protein S6 kinase alpha-3-like (LOC100496161), mRNA GAGTGAGAGAAGGGAGAAGAGCTGTGCTGGAGTGGTTCTGGCTTGCCGCGCAGTACCGGACAGCTCACGGTGACTCTAGGGGGGCGGACTGGAGCTCGGTCACTTTGGTGATTTTTGGGGACAATTGCTGGAATCACATCGGGTTGAAAAGATGCCGCTGGCGCAGCTGGCAGACCCGTGGCAGAAAGTGCCGGTGCAGAAAGTGGGAAGCGAGAATGGGCAGCAGTTTGCAGATGAATCAATGTGTGATGAAGACAATGAGAACAATGTATTTCTGGTTCGTAAAATCTCAGGAACTGATGCTGGGCAATTATATGCAATGAAAGTATTAAAAAAAGCTACACTTAAAGTCAGAGATCGTGTTAGAACAAAAATGGAGCGTGATATTTTGGTGGAAGTTAATCATCCGTTTATTGTGAAATTGCACTATGCTTTCCAAACAGAGGGCAAGCTGTACCTAATTTTGGATTTTCTCAGGGGTGGAGATTTGTTTACACGCTTATCCAAAGAGGTGATGTTCACAGAGGAAGATGTGAAGTATTACTTGGCAGAACTGGCACTAGCCTTAGACCATCTTCATTCTCTTGGAATCATTTATCGAGACCTGAAACCAGAAAACGAGCCAGCTGTTGTGTGTAGATTGGGAAGAATTTCAGAAGGAATGGCCTTGTGTAGCCATTCCCTCCAATGTCAGATAAAACATACTTTTGAAATGCTCACTGGTACCCTACCCTTTCAAGGAAAGGACAGAAAAGAAACCATGACCATGATTTTGAAAGCCAAACTTGGGATGCCTCAATTTTTAACTCCAGAAGCTCAGAGTCTCCTCCGCATGCTGTTCAAGAGAAATCCTACCAACAGACTAGGAGCAGGGCCAGATGGGGTTGAAGAGATTAAGAGACATCCATTTTTTGCCACAATTGATTGGAATAAACTGTATAGGAGAGAGAACCAGCCACCTTTTAAACCAGCCACTGGTGGACCAGAGGACACATTTTATTTTGATCCCGAGTTCACAGCAAAAACACCAAAAGATTCTCCTGGTATCCCAGCAAGTGCCAATGCACACCAGCTCTTCCGTGGGTTCAGCTTTGTTGCCATTACATCTGAGGATGAAAACCAAGCTATGCAAACGGTTGGGGTTCATGCTATTGTTCCACTTCATAGGAACAGTATCCAGTTCACAGATGGCTATGAGCTGAAGGAAGATATTGGTGTCGGTTCATATTCTATTTGCAAAAGGTGTATTCACAAGGGTACCAACATGGAATATGCAGTAAAGATTATTGACAAGAGCAAGAGAGATCCCACAGAGGAAATAGAAATACTGTTGCGATATGGGCAGCATCCCAATATTATTACGTTAAAAGACGTATATGATGATGGCAAATATGTGTATTTAGTAACGGAACTAATGAAAGGAGGGGAACTTTTAGATAAAATACTGCGGCAAAAGTTCTTCTCTGAGCGAGAGGCAAGTGCAGTGCTGCACACGATAACCAAAACTGTAGAATACCTCCATTCCCAGTGGGTCGTCCACAGGGATCTCAAGCCAAGCAATATTCTTTACGTGGATGAGTCTGGGAACCCTGAGTCTATTAGAATTTGTGACTTTGGCTTTGCAAAGCAACTCAGGGCAGAAAATGGCCTGCTTATGACTCCATGCTATACTGCAAATTTTGTGGCACCTGAGGTATTAAAGCGCCAAGGCTATGATGCAGCATGCGACATATGGAGTCTGGGTGTACTACTTTATACTATGCTGACAGGATACACTCCTTTTGCAAATGGGCCAGATGATACACCAGAAGAAATCCTAGCAAGAATAGGAAGTGGAAAGTTCTCTCTAAGTGGTGGCTATTGGAATTCTGTTTCAGATATTGCCAAGGACCTAGTTTCAAAGATGCTTCATGTGGATCCACATCAAAGGTTAACTGCAGCCCAAGTACTCAAGCACCCCTGGATAGTACACTGTGACCAGCTGCCTCAGTTTCAGCTAAACAGACAAGATGCTCCACACCTAGTAAAGGGAGCCATGGCAGCAACTTACTCTGCTTTGAACCTTAATCCATTGTCTCCCGTTCTGGAACCCGTTGGTCGTTCAACTCTGGCTCAGAGGAGAGGTATAAAGAAGATCACCTCCACTGCCCTGTGAAAGTCAAGTCATCTGTAAGAGCAGCCTGGAGCTGAAGATTCACAGCACAAAAAAAATATTAAAGCCAACAGTGATAGCACATATCCTAAAGACACTCCGGCAAGCAAATGCTCACTGTCTCTGCCGGCTCTCATAATCAATGCTGCTGCTTCTGTCTGTTCTCAGTAGTTAAGTGATGGAAAAACCCATCCAACCATGCCAGGACTTTGTCATCTGTACAATGGAACTGTCCTTGGGTGAATCCAATAGACTCTTCACCTCTCAAACTGAAGAATACACTGAAAATGATACAAAACACAAAAATATCTCAACGGTGAACAGCATTATTTTTATATAAGTATTCGTAGTCCTCCAAAATAACGGGTTCTAGGTTCACTTTTTATTTGAGCACTTGCATACTTTCAGCTCTTTGTTCTTTAAAGCGATGGATAAAACATGCCACTCAGCCTTCTGCCGTTGCTTCTGGCATTGCTGGATAGATTCAACGTCTTGCCAATCTACCCTTCCCCACATTTTGTGTTTTTTATTCTTCTTTTTAGATCATCTTTGCCTTGTCTTAATACAGAATAAGATATAGCCATGGAATGATTGTGTGGACTTCTCTGTAAAATACAACTGTGGAATTTCTCATGAATGTATCACAACCTAGATGAGCAACAAGAACTGTTACTGTGGGATGACCGCCGTAATAGCTTTCAAACTGCAATAAGTTCAAGCATTATGCCTCCAGCAAGCAGTACTAGGTGTATCTCTGACTTTGTTCATTGTCTTTTTTCGGGATTGTAGATCAGTAACCTTCCAATTTCCCACTTTGCTTTTCTTTGGTTTTTATTTTTTTGCATTGAAACGATGTACAACCTCATCAATCTGGTTCAGCAATCCACTTTTAAATCAGCTGTGCTTTTTAAGGGTTTCAGAGCACTTTAGCTCCCTAAACGGGTGCAAGCTTTAAAGCTGTCCTGGCATGAGCAGGCCACTGTATTCTGCTTCACGCATTAAGGCACAACCATAAAAAACAACCTGTTTGTTAGTGCCTGATGGCTGTAGGGAAAATGTCAGCACTTGTACTATTATAATTACTTGTTCTCAGAAGAAGGACTTTGCCAAAATCTTGCAAGGTTTGATATTGACTATGAGATGAACTGTTTATAAGACAAGCAGGCCTTTTGTGGATCTTTTGAGTTCTATGGCTAATGGCACACAAGGCAGTTTCTCTGCTGGTGGGTTTTATGTGGCCAATAAACACTTGACCCGTTTGTGCTGTTTTCTGATGACTTTAATGGAAGTCCTATGACACTGCTAGTACAAGCAGTTATCTGCCTGAAAATGCTCTAATGTGAATTTGGGGCACAGGCTTACTGGCTACTGGCGTGTCTCTGTTGGCTGAAGTACACTGGTGGAAAAAATGACCCTTGTGTCATTAGCTTAATGGTGGAGGTATTGCTTTTTTTTTTTTCTTCCCTTACAAACCACAGGGGGTAAATGAAATGAATTTCTCACTAAGAGCTTCCTTTTAAAGAGGTAATAAATAATTCAAGATGCCCCCTTTTAAGAGTTATGGATTTCAGGTGGTTTCTATTGCTGAAAGTGAATCTACCATGAAAGGTTAGGAGAACAAATGTGTGTGTTGTCCTCATCACGTTTGCAAAGGGTTAAGTGAATGGGGCAAGATGCATCTCTGTGCAGTTCTCGCTCCTCCTAAGCTGGCAAGTCTACAGCAAACGTAAAAAAACTGCCTCTCCGGAGGCACTTCCTGCATCAGTCACTTAACCCTCTGACAACCAGTAGCCCAGTACCAATGTTGTGAATGAATTCTGAAATTGCTCATACCAGCGCTTAGCAATTCTGCCATTTTTTTCAGCTTTATCTCCTGTTTAAAAAAATTGTTTTGAAATTTTACATTCTAGGACAGATAAGCACAAGCCACTGACATCATGAACATTGTGTAGAAAGCTGGTGCCTTTATTAGGAGGGTGAAGCCTCCCACTCCACGGGGGTTCCCTTTGCAGTTACACAGCTTCCCTTCATAAACCTGAATAAGCCATTTCACCTTGATTTGTGCTGCTCCTCTCCCTCCTTTATACAAGCTGAATACTAAGCCCACTCAGATTTTTTGAACCTTTACCAGCACTTAATAGTTTATGACTAAAGGTACTCCTGTCTCCCAATGGCGTATGAGTGTTGAACGGAAGTGCCAGCACCAAGAAGGATCTCTTGCACCTCACCAATTAGCTACTTAGAATATTGCATGACTTGATCATTTCAGAAGGGGATACTGTTTTTTTTTATTAATATGTTTCCTGGTAAGATTAGGGAAAAATATGTATGCTACGTTTATCATGTAATTCTCAAGCTAAAGGGAAGTTGTACACAAAGGGATGTAATTATTTTGCAGTTATCTCTGGTGGGAGGGACATTTTTTTTAAATAAATATAGAGAATATTTTTCTACACTTATATGTACAATCATTCTTTCTATTAGACTCTTTAGCTTGGCATGTCTGTACGTTTATAATCCATATTCTGGGAGTTAGTCTTTGTGGAAACTGCATAGCAGATGCTTTCACAGAGGTGAAACATTCTAGTACTACAAGGATAAAGCTGAATAGTCCTCCTCTCCTACCTATGAGCAGTCTCTTATGAATCCTGACATGTTACTCTGTCTAATAAACCCAAATGGTGATCGCTGCTTGTACATTTCACATCAACTGTTTTGTAATCCTCTAAGGAAACAGCAGTCCTTTATATAATAAACTTCCAAATACATAAACCAC	Refseq >NM_001090753\|Xenopus laevis ribosomal protein S6 kinase, 90kDa, polypeptide 3 (rps6ka3), mRNA GGACCATTGCTGGAATCTCATCCGCTTGGAAAGATGCCGCTGGCTCAGCTGGCAGACCCGTGGCAGAAAGTGCCGGTGCAGAAAGTGGAAAGCGAGAACGGGCAGCAGTTTGCAGATGAATCCATGTGTGAGGAGGACAATGAGAACAATGATGAAGGAAATATAAACGAAATTGCAATCACACACCATGTTAAAGAAGGCCATGAAAAGGCAGATCCTTCACAGTTTGAACTTCTAAAGGTTCTTGGGCAAGGCTCCTTTGGCAAGGTATTTCTGGTGCGTAAAATCTCAGGAACAGATGCTGGGCAATTATATGCAATGAAAGTATTAAAAAAGGCAACACTTAAAGTCCGAGATCGTGTCAGAACAAAAATGGAGCGTGATATTTTGGTGGAAGTTAATCATCCGTTTATTGTGAAATTGCACTATGCTTTCCAAACAGAGGGCAAGCTGTACCTAATTTTGGATTTTCTCAGGGGTGGAGATTTGTTTACACGCTTATCCAAAGAGGTAATGTTCACAGAAGAAGATGTGAAATATTACTTGGCTGAATTGGCACTAGCCTTAGACCATCTTCATTCTCTTGGAATCATTTATCGAGACCTAAAACCGGAAAACATATTACTTGATGAAGAAGGCCACATTAAATTAACCGATTTTGGCCTTAGTAAGGAGTCTATAGACCATGAAAAAAAAGCATATTCTTTCTGTGGAACGGTGGAATACATGGCTCCAGAGGTAGTAAATCGGCGAGGCCACACTCAGAGCGCAGACTGGTGGTCTTTTGGTGTTCTAATGTTTGAAATGCTCACTGGTACCCTACCCTTTCAAGGAAAGGACAGAAAAGAAACCATGACCATGATTCTGAAAGCCAAACTCGGGATGCCTCAGTTTTTAACTCCTGAAGCTCAGAGTCTTCTGCGCATGCTGTTTAAGAGAAATCCTACTAATAGACTAGGTGCTGGTCCAGATGGAGTTGAAGAGATTAAGAGACACCCTTTTTTTGTAACAATTGATTGGAATAAATTGTTTAGGAGAGAGATTCAGCCACCCTTTAAACCAGCCACTGGTGGACCCGAAGACACATTTTATTTCGATCCTGAATTCACAGCAAAAACGCCAAAAGATTCTCCTGGTATCCCAGCAAGTGCCAACGCACACCAGCTCTTCCGTGGGTTTAGCTTTGTTGCCATTTCATCTGAAGACGAAAACCAAGCTATGCAAACGGTTGGGGTTCATGCTATTGTTCCACTTCATAGGAACAGCATCCAGTTCACAGATGGCTACGAGCTAAAGGAAGATATTGGGGTGGGTTCCTATTCTATTTGCAAAAGGTGTATTCACAAGGGCACCAACATGGAATATGCGGTAAAGATTATTGACAAGAGCAAGAGAGATCCCACTGAGGAAATCGAAATACTGTTGCGATATGGGCAGCATCCCAATATCATTACGTTAAAAGATGTGTATGATGATGGAAAATATGTGTATTTAGTAACGGAACTTATGAAAGGAGGGGAACTTTTAGATAAAATACTGCGGCAAAAGTTCTTCTCCGAACGTGAGGCAAGTGCAGTGCTGCACACGATAACCAAAACCGCAGAATACCTCCATTCCCAGTGGGTCGTCCACAGGGATCTCAAGCCAAGCAATATTCTTTATGTGGATGAGTCTGGGAACCCTGAGTCTATTAGAATTTGTGACTTCGGCTTTGCAAAGCAACTCAGGGCAGAAAATGGTTTGCTTATGACTCCATGCTACACTGCAAATTTTGTGGCCCCTGAGGTGTTAAAGCGTCAAGGCTATGATGCAGCATGTGACATATGGAGTCTGGGTGTGCTGCTTTATACTATGCTGACAGGATACACTCCTTTTGCAAACGGGCCAGAAGATACACCAGAAGAAATCTTAGCAAGAATAGGAAGTGGAAAGTTCTCTCTTAGTGGCGGCTATTGGAATTCTGTTTCAGATATCGCCAAGGACCTAGTTTCAAAGATGCTTCATGTGGATCCACATCAACGATTAACTGCAGCCCAGGTCCTTAAACACCCCTGGATAGTACACTGTGACCAGCTGCCTCAGTTTCAGCTGAACAGACAAGATGCTCCACATCTAGTAAAGGGAGCCATGGCAGCAACTTATTCTGCCTTGAACCTTAATCCAATGTCTCCAGTACTGGCACCTGTTGGTCGTTCTACTCTGGCTCAGAGGAGGGGAGTAAAGAAGATTACCTCCACTGCCCTGTGAAAGTCACGTCATCTAGTAAGAGCAACCTGGAGCTGAAGATTCACAGCACAATAAAAAGCCAACAGTGAAAGCACATATCATAAAGACACTCCGGCAAGCAAATGCTCACCGTCTCTGCCGGCTCTCATAATCAATGCTGCTGCTTTTGTCTCTGTTCTCAGTAGTTCTGTGCCGGGGACTTTCGTCTCTAAAATGGAACTGTCCTTTGGTGAATGCAACAGATTATTCACCTCTGCAACTGAAGAATACACTGAAAATGAAACAAACCAATAAATCTCAACGCTGAACAGCATTCGTTTTATAAGAAGTATTTGTAGTCCTCCAACGTAACAGGTTCTAGGTTCACTTTTTTTTATTTGAGCACTTGCATACTCTCGACTCTTTTGTTCCTTAAATTGATTTATACAACATGCCACTCAGCCTTCTGCACTTGCTTCTGGCAGATTCAACTTTCAAGTGAAACTTCTTGCCAATATACATCTGTTTTTTTGTTTTTTTTTTATTCTTATTAGATTGATCATCTTTGCCTTGTCTTAATACACAATAAGATATAGTCATGGAATGATTGTGTGGACTTGTCTGTAAAAGAAAAGAACTACAACTGTGGAATTTCTCATGAATGTATCACGACCTAGATCAGCAACGAGAACCGACTCCCGCATGTAACTGCGGGAAGACTGCCAGAATAGCTTTCAAACTGCAATAAGTTCAAGCATTATGCCTCCAGCAAGCAGTACTAGGTGTATATTTGACTTTATTATGTGTCTTTTTGGGATTGTAGATCAGTAACCTTCCACTTTCAGACTTTGCTTCTTTGCTTTTATTTTATTTTTTACGGTTTCTTGGATTGAAAATGATGCATACAACCATAAATATATATAAATATAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002936090\|PREDICTED: ribosomal protein S6 kinase alpha-3-like [Xenopus (Silurana) tropicalis] MPLAQLADPWQKVPVQKVGSENGQQFADESMCDEDNENNVFLVRKISGTDAGQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKYYLAELALALDHLHSLGIIYRDLKPENEPAVVCRLGRISEGMALCSHSLQCQIKHTFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLTPEAQSLLRMLFKRNPTNRLGAGPDGVEEIKRHPFFATIDWNKLYRRENQPPFKPATGGPEDTFYFDPEFTAKTPKDSPGIPASANAHQLFRGFSFVAITSEDENQAMQTVGVHAIVPLHRNSIQFTDGYELKEDIGVGSYSICKRCIHKGTNMEYAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMKGGELLDKILRQKFFSEREASAVLHTITKTVEYLHSQWVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDIAKDLVSKMLHVDPHQRLTAAQVLKHPWIVHCDQLPQFQLNRQDAPHLVKGAMAATYSALNLNPLSPVLEPVGRSTLAQRRGIKKITSTAL	Refseq >NP_001084222\|ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Xenopus laevis] MPLAQLADPWQKVPVQKVESENGQQFADESMCEEDNENNDEGNINEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVRKISGTDAGQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKYYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLTPEAQSLLRMLFKRNPTNRLGAGPDGVEEIKRHPFFVTIDWNKLFRREIQPPFKPATGGPEDTFYFDPEFTAKTPKDSPGIPASANAHQLFRGFSFVAISSEDENQAMQTVGVHAIVPLHRNSIQFTDGYELKEDIGVGSYSICKRCIHKGTNMEYAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMKGGELLDKILRQKFFSEREASAVLHTITKTAEYLHSQWVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPEDTPEEILARIGSGKFSLSGGYWNSVSDIAKDLVSKMLHVDPHQRLTAAQVLKHPWIVHCDQLPQFQLNRQDAPHLVKGAMAATYSALNLNPMSPVLAPVGRSTLAQRRGVKKITSTAL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.33175
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	RPS6KA3	OMIM:303600
mouse		MGI	Rps6ka3	All(4) Targeted, knock Out(3) Targeted, other(1)
zebrafish		ZFIN ZFIN	rps6ka3a rps6ka3b	1 Lines(s)

Publications
First:		A protein kinase from Xenopus eggs specific for ribosomal protein S6. [Proc Natl Acad Sci U S A 1985]
Most recent:		Oncogenic Ras suppresses Cdk1 in a complex manner during the incubation of activated Xenopus egg extracts. [Arch Biochem Biophys 2013]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		ATP binding cAMP-dependent protein kinase activity cAMP-dependent protein kinase regulator activity More[+] protein kinase CK2 activity protein kinase CK2 regulator activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity serine-type endopeptidase inhibitor activity
Biological:		protein amino acid phosphorylation
Cellular Component:		cAMP-dependent protein kinase complex protein kinase CK2 complex
EC:		now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
KOG:		[T] Ribosomal protein S6 kinase

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		Str.4373.1.S1_at	Xl.575.1.S1_at
Affymetrix 2.0			Xl2.33175.1.S2_at

Symbol legend[+]