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Summary Expression Gene Literature (27) GO Terms (40) Nucleotides (93) Proteins (31) Interactants (351) Wiki
XB-GENEPAGE-481046
Gene Symbol:
stat3.1

Gene Name:
signal transducer and activator of transcription 3, gene 1

Synonyms:
Xstat3 , aprf , hies , Stat3 ( Add synonyms , Nomenclature history )

Gene Function:
intracellular signaling

Protein Function :
Transcription factor that binds to target promoter sequences and activates transcription upon il6st/gp130 stimulation. Mediates ventralization of embryos, at least in part via inhibition of smad2 signa...[+]



Interactants:
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Diseases: 


Disease Ontology:
Job's syndrome

OMIM:
HYPER-IgE RECURRENT INFECTION SYNDROME, AUTOSOMAL DOMINANT [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-481047 XB-GENE-865436 XB-GENE-17332303
Gene Symbol stat3.1 stat3.1.L stat3.1.S
Chromosome Chr10 chr9_10L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100498278
779100
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine stat3.1 stat3.1.L stat3.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards STAT3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Stat3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Stat3 Ensembl
zebrafish
ZFIN, AGR stat3 ZFIN Ensembl
chicken
GEISHA STAT3 Ensembl
fruit fly
worm
Publications
First Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4., Dev Biol 1999                
Most Recent The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development., J Biol Chem 2020                  
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 27 terms 21 terms 0 term
PANTHER stat3.1
KEGG Pathways K04692
KOG [KT] STAprotein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks stat3.1
Antibodies Phospho-Stat3 (Tyr705) Ab1 , phospho-Stat3 Ab2 , stat3 Ab3 Phospho-Stat3 (Tyr705) Ab1 , phospho-Stat3 Ab2 , stat3 Ab3 Phospho-Stat3 (Tyr705) Ab1 , phospho-Stat3 Ab2 , stat3 Ab3
Morpholinos stat3.1 MO1 stat3.1 MO1 stat3.1 MO1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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