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Summary Expression Gene Literature (465) GO Terms (18) Nucleotides (144) Proteins (38) Interactants (513) Wiki
XB-GENEPAGE-481105
Gene Symbol:
hdac3

Gene Name:
histone deacetylase 3

Synonyms:
Rpd3 , HDm , HDAC , XRpd3 ( Add synonyms , Nomenclature history )

Gene Function:
regulation of gene expression

Protein Function :
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an importan...[+]


InterPro :
Ureohydrolase dom sf , His deacetylse , His deacetylse 1 , His deacetylse dom [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-481106 XB-GENE-17346498 XB-GENE-6256296
Gene Symbol hdac3 hdac3.L hdac3.S
Chromosome Chr3 chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 549637
432017
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hdac3 hdac3.L hdac3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HDAC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hdac3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hdac3 Ensembl
zebrafish
ZFIN, AGR hdac3 ZFIN Ensembl
chicken
GEISHA HDAC3 Ensembl
fruit fly
FLYBASE Hdac3 Ensembl
worm
Publications
First Xenopus HDm, a maternally expressed histone deacetylase, belongs to an ancient family of acetyl-metabolizing enzymes., Gene 1997          
Most Recent Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis., Dev Comp Immunol 2021  
All View All Papers 2 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 0 term 9 terms
PANTHER hdac3
KEGG Pathways K11404 K11404
KOG [B] Histone deacetylase complex, catalytic component RPD3
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hdac3
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list