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Summary Expression Gene Literature (26) GO Terms (30) Nucleotides (490) Proteins (32) Interactants (676) Wiki
XB-GENEPAGE- 481296

Gene Symbol: id2

Gene Name: inhibitor of DNA binding 2

Synonyms: xid2
Add Xenopus synonyms , Nomenclature history


Gene Function: transcriptional regulator

Protein Function :
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA bindin...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
1/3
 

Xenbase Gene ID XB-GENE-481297 XB-GENE-481302 XB-GENE-17341008
Gene Symbol id2 id2.L id2.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.20518 Xl.492
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 16 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine id2 id2.L id2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ID2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Id2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR id2a id2b ZFIN Ensembl
chicken
GEISHA ID2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: XIdx, a dominant negative regulator of bHLH function in early Xenopus embryos. [Mech Dev 1995]
Most recent: Xenopus SOX5 enhances myogenic transcription indirectly through transrepression. [Dev Biol 2018]
View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 29 terms 24 terms 23 terms
PANTHER id2
KEGG Pathways K17693 K17693 K17693
KOG [K] Transcription factor NeuroD and related HTH proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino id2 MO1 id2 MO1 id2 MO1
ORF id2 ORF1 , id2 ORF1 id2.L ORF1 id2.S ORF1
Affymetrix 1.0 Str.20518.1.S1_at [+] Xl.492.1.S1_at
Affymetrix 2.0 Xl2.492.1.S1_at

Symbol legend[+]
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Version: 4.9.2
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556