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Summary Expression Gene Literature (34) GO Terms (10) Nucleotides (158) Proteins (25) Interactants (397) Wiki
XB-GENEPAGE- 481306

Gene Symbol: smad6

Gene Name: SMAD family member 6

Synonyms: madh6 , Xsmad6
Add Xenopus synonyms , Nomenclature history

Gene Function: signal transduction, TGF-beta pathway

Protein Function :


Interactants: Loading ...

Disease Ontology:
   AORTIC VALVE STENOSIS

OMIM Diseases:
   AORTIC VALVE DISEASE 2; AOVD2 [+]
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Xenbase Gene ID XB-GENE-481307 XB-GENE-481311 XB-GENE-17331300
Gene Symbol smad6 smad6.L smad6.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.52355 Xl.2593
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 12 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine smad6 smad6.L smad6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas073h08      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMAD6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Smad6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR smad6a smad6b ZFIN Ensembl
chicken
GEISHA SMAD6 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. [Nature 1997]
Most recent: Axis Patterning by BMPs: Cnidarian Network Reveals Evolutionary Constraints. [Cell Rep 2015]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 7 terms 7 terms
PANTHER smad6
KEGG Pathways K04677 K04677 K04677
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino smad6 MO1 , smad6 MO2 smad6 MO1 , smad6 MO2 smad6 MO1 , smad6 MO2
ORF smad6.L ORF1
Affymetrix 1.0 Str.2540.1.S1_at Xl.2593.1.S1_at
Affymetrix 2.0 Xl2.2593.1.S1_at

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.2
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556