Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (85) GO Terms (5) Nucleotides (110) Proteins (27) Interactants (489) Wiki
XB-GENEPAGE- 481335

Gene Symbol: isl1

Gene Name: ISL LIM homeobox 1

Synonyms: islet-1 , Xisl-1 , Xislet-1 , islet1
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:


Interactants: YYY

OMIM Disease Associations:
1/3
 
Xenbase Gene ID XB-GENE-481336 XB-GENE-17340675 XB-GENE-865118
Gene Symbol isl1 isl1.L isl1.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.48718 Xl.48014 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 68 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine isl1 isl1.L isl1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ISL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Isl1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN isl1 ZFIN Ensembl
chicken
GEISHA ISL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Regulation of vertebrate neural cell fate by transcription factors. [Curr Opin Neurobiol 1996]
Most recent: Fgfr signaling is required as the early eye field forms to promote later patterning and morphogenesis of the eye. [Dev Dyn 2017]
View All Papers 22 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 5 terms
EC
PANTHER isl1
KEGG Pathways K09370
KOG [R] Transcription factor, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 4 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Isl1 Ab1 , Isl1/2 Ab1 , isl1 Ab2 isl1 Ab2
Morpholino isl1 MO1 isl1 MO1 isl1 MO1
ORF isl1 ORF1
Affymetrix 1.0 StrJgi.848.1.S1_at [+]
Affymetrix 2.0 Xl2.55881.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556