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Summary Expression Gene Literature (515) GO Terms (24) Nucleotides (161) Proteins (37) Interactants (1187) Wiki
XB-GENEPAGE-481352
Gene Symbol:
frzb

Gene Name:
frizzled related protein

Synonyms:
Frzb-1 , xfrzb , fre , os1 , fzrb , fiz , frp-3 , frzb1 , sfrp3 , srfp3 , frzb-pen ( Add synonyms , Nomenclature history )

Gene Function:
secreted wnt antagonist

Protein Function :


InterPro :
HnRNPA1 , RBD domain sf , hnRNPA2B1 RRM1 , hnRNP A2/B1 [+]

Interactants:
Loading ...

Diseases: 


OMIM:
OSTEOARTHRITIS SUSCEPTIBILITY 1; OS1

External Links:
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Xenbase Gene ID XB-GENE-481353 XB-GENE-17332603 XB-GENE-865117
Gene Symbol frzb frzb.L frzb.S
Chromosome Chr9 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448021
399085
734982
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine frzb frzb.L frzb.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FRZB OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Frzb MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Frzb Ensembl
zebrafish
ZFIN, AGR frzb ZFIN Ensembl
chicken
GEISHA FRZB Ensembl
fruit fly
worm
Publications
First FTZ-F1-related orphan receptors in Xenopus laevis: transcriptional regulators differentially expressed during early embryogenesis., Mol Cell Biol 1994  
Most Recent The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Elife 2020                                                                      
All View All Papers 14 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 6 terms 7 terms
PANTHER frzb
KEGG Pathways
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks frzb
Morpholinos frzb MO1 frzb MO1 frzb MO1
ORFs frzb ORF1 frzb ORF1 frzb.S ORF1
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list