Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (24) GO Terms (18) Nucleotides (169) Proteins (34) Interactants (484) Wiki
XB-GENEPAGE-481381

Gene Symbol: foxc2

Gene Name: forkhead box C2

Synonyms: fd-4 , XFD-4 , MFH-1 , Mfh1 , fkh7 , foxc2-a , foxc2-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: forkhead domain transcription factor

Protein Function :
Transcriptional activator. May be involved in the dorso-ventral patterning of the mesoderm.

Interactants: Loading ...
Disease Ontology: YELLOW NAIL SYNDROME [+]

OMIM Diseases: LYMPHEDEMA, HEREDITARY, II; LMPH2 [+]
1/3
 
Xenbase Gene ID XB-GENE-481382 XB-GENE-865122 XB-GENE-6254394
Gene Symbol foxc2 foxc2.L foxc2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Swiss-Prot Refseq Swiss-Prot TrEMBL Swiss-Prot Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine foxc2 foxc2.L foxc2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FOXC2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Foxc2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA FOXC2 Ensembl
fruit fly
worm
WORMBASE
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most recent Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Dev Biol 2018                      
All View All Papers 2 paper(s) referencing morpholinos 24 paper(s) referencing OMIMs 24 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 11 terms 11 terms
PANTHER foxc2
KEGG Pathways K09396 K09396 K09396
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Morpholino foxc2 MO1 foxc2 MO1 foxc2 MO1
ORF foxc2 ORF1 foxc2.L ORF1
Affymetrix 1.0 Str.2696.1.S1_at [+] Xl.508.1.S1_at
Affymetrix 2.0 Xl2.20334.1.S1_at Xl2.508.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.10.1


Major funding for Xenbase is provided by grant P41 HD064556