map3k7 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (26)

Nucleotides (173)

Interactants (77)

XB-GENEPAGE-481529

Gene Symbol: map3k7 Gene Name: mitogen-activated protein kinase kinase kinase 7 Synonyms: xTAK1, MAPKKK, tak1 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: mapk1(16) , nr2c2(15) , tgfb1(6) , jun(4) , mapk8(4) , mos(4) , nlk(4) View All

XB-GENE-481530

XB-GENE-481534

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001100261\|Xenopus (Silurana) tropicalis mitogen-activated protein kinase kinase kinase 7 (map3k7), mRNA GCGGCTACAGTAGTAGCAAGAGAGCCCTCCCCTCTTCCACCACAGGCCCTGGCTCCAAGCAGGCTAGGCCCAGCAGCCCAGAAGGGGGTTACCTGGTCCTTGATGGGCCGGGGCCGCCCGTCACGTACAAGTATTACGGTGGCTCCTGTTAAACCCGCTCTGTTTTCCCCAGCTGTGTACCCCGGCTTCCGCCGGTGGGGTCCCCGATTTCTCTTGTAAGGGCACGGCATGTCTGCCGCCTCTGCTGACATGATTGAGACTCCACCGGTGCTAAACTTTGAGGAGATCGACTACAAGGAGATAGAGGTGGAAGAGGTAGTTGGAAGAGGAACCTTTGGTGTTGTCTGCAAAGCCAAATGGCGAGGAAAGGATGTGGCAATTAAACAAATTGAAAGTGAATCTGAAAGGAAAGCCTTTATTGTTGAGCTGCGGCAGTTGTCTCGTGTTAACCATCCCAATATTGTCAAGTTGTATGGAGCCTGCCTAAATCCTGTATGTTTAGTAATGGAATATGCAGAAGGCGGTTCCCTGTACAATGTTTTGCATGGAGCTGAACCACTGCCGTACTATACAGCTGCGCATGCAATGAGTTGGTGTTTACAATGTGCCCAAGGAGTCGCATATTTACATAGCATGAAGCCAAAGGCTCTAATTCACAGGGACCTCAAACCACCAAACTTGCTGCTGGTAGCTGGAGGCACTGTTCTTAAGATTTGTGACTTTGGTACAGCCTGTGATATTCAGACTCACATGACTAATAACAAAGGAAGCGCAGCATGGATGGCTCCAGAAGTTTTTGAAGGTAGCAACTACAGTGAGAAATGTGATGTATTTAGTTGGGGAATCATTCTATGGGAAGTAATAACCCGAAGAAAACCTTTTGATGAAATTGGTGGCCCAGCATTCCGTATAATGTGGGCTGTTCACAATGGTACTCGTCCACCATTAATTAAAAATTTGCCTAAGCCTATTGAAAGCTTAATGACTCGCTGCTGGTCCAAAGATCCCCCACAAAGACCTTCAATGGAGGAGATTGTCAAGATAATGACACATCTTATGCAGGTATGTTGCCATTGAAGATATGTTTTTGCCTTTAAAGGAAAAGTAACAAAAACATTTCCAATTACAAATATACTTTTGAAACACTCTTATCTACTTATATAATAGAGCCAAATTGCAATTTTATGAGTGGTTATTGAATAAATTGCATTACCTTGGCTGTATAGGGCATAGTTAAAAAAGGCGATGTGACGACTGCTTTACTTCTGGTTAAAATTGGAAGTTCATTTCCTGCATTTTCTAGCATACAAAGAGCCTGCTTTAAAAGTGATTTAAAGGTTTTTTCATGTCCATTCTGGGAGAGGGATGGGTGATGGAGGTCTTCTTATCTCCTACTCTGTTTGGATTTATGTGTGAGTGGAGCGCTGCTGTGGTTGCACTGGGAGGGGGAGGATGGGGAAGTTAGTCACGAGAGAAGCTGCAGCCTGAGCCCTATCAATATATGGTTATTTATTTAAAATCTACTTATGACATCAACATTTCAGTGATGACAAATATGATAATAAAAGTGTTTAGAAGGCATATGTTCAATGTCCTTTAAGCAACTTTCTGCAAAACTCTCAAAGGATTTGGGTTTTATAAAATAAGTGCTCAAATTTCCAGGGCAAGCACATTGGCTTCATGGTTCTTATCTCTTGACGGTGAGATTAGTCGCCATCCTACCAGCAAGAATGTAAATCGCCTATGGAATGGTTTCCTTTCAAGGCAACTTTGGCGTATGCCATCCCACCTGCAATTTACATTCTTGCCGGTGGGATGGCATTGCAGGGAGATTAGTCTCCTGCGGCAACAGAGATTTGTCGTGGGGCGACTAATCTCCCCATCTGCCCTAAACATTGTCTCAATCAAAAAAAAAAAAAAA	Refseq >NM_001090890\|Xenopus laevis mitogen-activated protein kinase kinase kinase 7 (map3k7), mRNA GAATTCGGCACGAGGCCCCCACTATCGGCGCGCTCTGTACGAGGCCTGTGCGTATGTGCTTCTACCTGTATGGTCGGATCGGAAGTTGGCAAGCGCTTCTGCGGCCACAGTAGCAGCGAGAGAGCCCTTCGCTCTTCCATCACAGGCCCTGGCTCTAAGCAGGCTAGGCCCAGCAGCCCAGAAGGGGGTTACCTGGTCCTTGCTGGGCCGGGGCCGCCCGTCACTTCCAAGTATTACGGTGGCTCCTGCTAAGCCCGCTGGGTGCAGGGCTCGGTGTTTTGCAGCTGTGTACCCCGGCTTCCGCCGGTGGGGTCCCCGATTTCTCGAGTAAGGGCGCGGCATGTCTGCCACCTCTGCTGAAATGATTGAGACTCCACCGGTGCTGAACTTTGAGGAGATCGACTACAAGGAGATTGAGGTGGAAGAGGTAGTTGGAAGAGGAACCTTTGGTGTTGTCTGCAAAGCTAAATGGCGAGGAAAAGATGTGGCAATCAAACAAATTGAAAGCGAATCTGAAAGGAAAGCCTTTATTGTTGAGCTGCGACAGTTGTCTCGTGTTAACCATCCCAATATTGTCAAGTTGTATGGAGCCTGCCTAAATCCGGTATGTTTAGTGATGGAGTATGCAGAAGGAGGTTCATTGTACAATGTTTTGCATGGAGCTGAACCGCTGCCTTACTATACAGCTGCTCATGCAATGAGTTGGTGTTTACAATGTGCCCAAGGAGTTGCATATTTACATAGCATGAAGCCGAAGGCTCTAATTCACAGGGACCTCAAACCACCAAACTTGCTGCTGGTAGCTGGAGGCACCGTTCTTAAGATTTGTGACTTTGGTACAGCCTGTGATATTCAGACTCACATGACTAATAACAAAGGAAGTGCAGCATGGATGGCTCCAGAAGTTTTTGAAGGTAGCAATTACAGCGAGAAATGTGACGTATTTAGTTGGGGAATAATTCTTTGGGAAGTAATAACCCGAAGAAAACCTTTCGATGAAATTGGTGGTCCAGCGTTCCGTATCATGTGGGCTGTTCACAATGGTACTCGCCCACCATTAATTAAAAATTTGCCTAAGCCTATTGAAAGCTTAATGACTCGCTGCTGGTCCAAAGATCCCCCACAAAGACCTTCAATGGAGGAGATTGTCAAGATAATGACTCATCTAATGCAGTATTTTCCTGGAGCGGATGTTTCCTTACAGTATCCTTGTCAGTACTCAGATGAAGGGCAAAGTAATTCTGCCACAAGTACAGGTTCCTGCATTGATATTACATCGACTAATACTAGTAACAAGAGTGACATCCATATAGAACCTGGTGATTTCCAAGCAAGTGCGAGTAATGACACAATCAAACGAATTGAATCAAAGCTTGCACAACACTTGAAAAATCAAGCAAAGCAAACGGGTGAATCGGGTCGATTGAGTTTGCCTCCCTCTCGGGGTAGCAGTGTAGAGAGCCTGTCTGAAATACGAGGTAGACCACCATCTACTCTGGGTACATCTGAGGGGAAACGAATGAGTGCGGACATGTCTGAATTAGAAGCAAGAATTTCTGCAAGTACAGCATATGTCAAGCCTAAACGAGGCCACCGTAAAACTGCTTCATTTGGCAACATTCTGGATGTCCCAGAGATCATCATTACAGCAGGAAACGGGCAGCAGAGGCGCAGATCTGTACAAGACCTCACTATTGTTGGAACAGAGTCCAGTCAGGAGAGCAGAAACAGTAGCAGATCGTCTAGTCCAAGTGTGAGGATGATTACTACCTCAGGACCAACCCCAGACAAGCCCCCACGTGGCCTTCCATGGGCCCCCGATGAATCTTCAGATACAAATGGATCTGATAACTCCATACCTATGGCATACCTTACACTGGATCATCAGTTACAGCCTCTAGCACCGTGTCCAAACTCTAAAGAATCTATGGCTGTGTTTGAACAACACTGCAAAATGGCACAGGAGTACATGAAAGTGCAGACCGAAATCGCTTTATTGCTGCAAAGAAAGCAAGAGCTTATTGCAGAACTAGATCAGGATGAAAAAGACCAGCAGAACACATCGCGTCTGGTGCAAGAACACAAAAAGCTTTTAGATGAAAATAAAAGCCTTTCCACATATTATCAGCAATGTAAAAAACAGTTGGAAGTCATCCGAAGTCAGCAGCAGAAACGACAAGGAACCTCCTGATTTTCTTGAACTTCTTCTCCGTTAACATTTTGCTATGGAGCAGGATGGCTGCAAACTTGACTTCCTTGCTTGCTGGAGCATGAGGATGGACAAGTCTCTTCAGACCGTGAAGCTGCTGTTAGGAGTACTGTGAACTCTATATGCTTCATGACTCTGGACTCTCCACTAGTGTTATCTATATGAAGAGCTGTGATATTTTTGCCTATACCCTTGGCAGTGTTCCCTTCCCCTCCCCCCTTCCTTATCGTAAGGCTGGTGGGGACTTTGTTCTAAAGTAAAAGGACACTATGAAGTTTGCAGGATAAGCATTGCTGCTGCAACAAGCTGAAAGTTCTAAAATTATGTTCAAGGTGGCTGTCATTAGTTAAAAGTATGTACCATATACTCTCTGTATGTCTGCAATTTTCTCTGTATGCCCTGGTACTATTACAATTGCATTAACCCCTTTAGTGCCGTACCATGTCGTGGTAACATCTGTTGGAAAACTACGGCGCCAAAAAGGATTTTTTTTTTCCTGTGTGCAGAAATAATACAGCGGGTGAAAAGACTTGTATAAATGTAATGGAATTAAAGCATTGAATAAAATTGGATTTATTTAAAAAAAAAAAAAAAAAACTCGAC
Protein		Refseq >NP_001093731\|mitogen-activated protein kinase kinase kinase 7 [Xenopus (Silurana) tropicalis] MSAASADMIETPPVLNFEEIDYKEIEVEEVVGRGTFGVVCKAKWRGKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCAQGVAYLHSMKPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPPQRPSMEEIVKIMTHLMQVCCH	Refseq >NP_001084359\|mitogen-activated protein kinase kinase kinase 7 [Xenopus laevis] MSATSAEMIETPPVLNFEEIDYKEIEVEEVVGRGTFGVVCKAKWRGKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCAQGVAYLHSMKPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPPQRPSMEEIVKIMTHLMQYFPGADVSLQYPCQYSDEGQSNSATSTGSCIDITSTNTSNKSDIHIEPGDFQASASNDTIKRIESKLAQHLKNQAKQTGESGRLSLPPSRGSSVESLSEIRGRPPSTLGTSEGKRMSADMSELEARISASTAYVKPKRGHRKTASFGNILDVPEIIITAGNGQQRRRSVQDLTIVGTESSQESRNSSRSSSPSVRMITTSGPTPDKPPRGLPWAPDESSDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELIAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.18072	Xl.274
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	MAP3K7
mouse		MGI	Map3k7	All(8) Targeted, knock Out(2) Targeted, other(5) Gene Trapped(1)
zebrafish		ZFIN	map3k7	1 Lines(s)

Publications
First:		Phosphorylation of Xenopus mitogen-activated protein (MAP) kinase kinase by MAP kinase kinase kinase and MAP kinase. [J Biol Chem 1993]
Most recent:		TAK1 promotes BMP4/Smad1 signaling via inhibition of erk MAPK: a new link in the FGF/BMP regulatory network. [Differentiation 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		3-phosphoinositide-dependent protein kinase activity AMP-activated protein kinase activity ATP binding More[+] DNA-dependent protein kinase activity G-protein coupled receptor kinase activity IkappaB kinase activity JUN kinase activity JUN kinase kinase activity JUN kinase kinase kinase activity Janus kinase activity MAP kinase 1 activity MAP kinase 2 activity MAP kinase activity MAP kinase kinase activity MAP kinase kinase kinase activity MAP kinase kinase kinase kinase activity MAP/ERK kinase kinase activity MP kinase activity NF-kappaB-inducing kinase activity SAP kinase activity atypical protein kinase C activity cGMP-dependent protein kinase activity calcium-dependent protein kinase C activity calmodulin-dependent protein kinase activity casein kinase I activity casein kinase activity cobinamide kinase activity cyclic nucleotide-dependent protein kinase activity cyclin-dependent protein kinase activating kinase activity cyclin-dependent protein kinase activating kinase regulator activity cyclin-dependent protein kinase activity cyclin-dependent protein kinase regulator activity diacylglycerol-activated phospholipid-dependent protein kinase C activity elongation factor-2 kinase activity eukaryotic elongation factor-2 kinase activator activity eukaryotic elongation factor-2 kinase regulator activity eukaryotic translation initiation factor 2alpha kinase activity galactosyltransferase-associated kinase activity glycogen synthase kinase 3 activity multifunctional calcium- and calmodulin-regulated protein kinase activity non-membrane spanning protein tyrosine kinase activity phenol kinase activity phosphatidylinositol phosphate kinase activity phosphofructokinase activity phosphoinositide 3-kinase activity phosphorylase kinase activity phosphorylase kinase regulator activity phosphotransferase activity, alcohol group as acceptor protein kinase C activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity receptor signaling protein serine/threonine kinase activity receptor signaling protein tyrosine kinase activity ribosomal protein S6 kinase activity transmembrane receptor protein kinase activity transmembrane receptor protein serine/threonine kinase activity transmembrane receptor protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:
EC:		Phosphotransferases with an Alcohol Group as Acceptor
KOG:		[T] Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs

Reagents		tropicalis	laevis
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.3144.1.S1_at	Xl.274.1.S1_at [+] Xl.24092.1.A1_x_at
Affymetrix 2.0			Xl2.274.1.S1_at [+] Xl2.24092.1.A1_x_at

Symbol legend[+]