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Summary Expression Gene Literature (157) GO Terms (5) Nucleotides (103) Proteins (25) Interactants (957) Wiki
XB-GENEPAGE- 481643

Gene Symbol: dkk1

Gene Name: dickkopf WNT signaling pathway inhibitor 1

Synonyms: dickkopf-1 , Xdkk-1 , dkk-1 , dkk , xdkk1 , Dickkopf1
Add Xenopus synonyms , Nomenclature history


Gene Function: secreted wnt antagonist

Protein Function:


Interactants: YYY

OMIM Disease Associations:
1/2
 
Xenbase Gene ID XB-GENE-481644 XB-GENE-17337757 XB-GENE-865473
Gene Symbol dkk1 dkk1.L dkk1.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq TrEMBL NCBI Protein TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.15023 [+] Xl.251
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 32 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dkk1 dkk1.L dkk1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DKK1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Dkk1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN dkk1b dkk1a ZFIN Ensembl
chicken
GEISHA DKK1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. [Nature 1998]
Most recent: Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover. [Dev Cell 2017]
View All Papers 44 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 3 terms 5 terms
EC
PANTHER dkk1
KEGG Pathways K02165 K02165 K02165
KOG [T] Proteins containing Ca2+-binding EGF-like domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Dkk1 Ab1 Dkk1 Ab1
Affymetrix 1.0 Str.15023.1.S1_a_at [+] Xl.251.1.S1_at
Affymetrix 2.0 Xl2.251.1.S1_at [+]

Symbol legend[+]

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