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Summary Expression Gene Literature (352) GO Terms (5) Nucleotides (385) Proteins (31) Interactants (680) Wiki
XB-GENEPAGE-481724
Gene Symbol:
a2m

Gene Name:
alpha-2-macroglobulin

Synonyms:
endodermin , Alpha2-macroglobulin , endod ( Add synonyms , Nomenclature history )

Gene Function:
protease inhibitor

Protein Function :


InterPro :
Laminin N , Laminin EGF , Laminin N sf , EGF-like dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Alzheimer's disease

OMIM:
ALZHEIMER DISEASE; AD [+]

External Links:
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Xenbase Gene ID XB-GENE-481725 XB-GENE-17333199 XB-GENE-6252734
Gene Symbol a2m a2m.L a2m.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 619586
108695707
100158443
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine a2m a2m.L a2m.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards A2M OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR A2m MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR A2m Ensembl
zebrafish
chicken
GEISHA A2M Ensembl
fruit fly
worm
Publications
First Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps., EMBO J 1996  
Most Recent Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Aquat Toxicol 2020  
All View All Papers 22 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 0 term 3 terms
PANTHER a2m
KEGG Pathways K03910
KOG [O] Alpha-macroglobulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks a2m
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list