Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (25) Nucleotides (116) Proteins (31) Interactants (83) Wiki
XB-GENEPAGE-481749
Gene Symbol:
angptl4

Gene Name:
angiopoietin like 4

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
secreted endothelial growth factor

Protein Function :


InterPro :
Integrin alpha , Integrin alpha N , Integrin alpha-2 , Int alpha beta-p [+]

Interactants:
Loading ...

Diseases: 


OMIM:
PLASMA TRIGLYCERIDE LEVEL QUANTITATIVE TRAIT LOCUS; TGQTL

External Links:
1/5
 
Xenbase Gene ID XB-GENE-481750 XB-GENE-6487565 XB-GENE-17333796
Gene Symbol angptl4 angptl4.L angptl4.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492339
108712679
108706856
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein TrEMBL NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine angptl4 angptl4.L angptl4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ANGPTL4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Angptl4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Angptl4 Ensembl
zebrafish
ZFIN, AGR angptl4 ZFIN Ensembl
chicken
GEISHA ANGPTL4 Ensembl
fruit fly
worm
Publications
First Angiopoietin-like 4 Is a Wnt Signaling Antagonist that Promotes LRP6 Turnover., Dev Cell 2017                                  
Most Recent The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Elife 2020                                                                                                
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 24 terms 4 terms 4 terms
PANTHER angptl4
KEGG Pathways K08767 K08767 K08767
KOG [R] Ficolin and related extracellular proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks angptl4
Morpholinos (on-target & off-target) angptl4 MO1 angptl4 MO1 angptl4 MO1
Clones Horizon Horizon Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info