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Summary Expression Gene Literature (27) GO Terms (8) Nucleotides (44) Proteins (22) Interactants (164) Wiki
XB-GENEPAGE- 481755

Gene Symbol: il1b

Gene Name: interleukin 1 beta

Synonyms: IL-1B , interleukin-1-beta , IL-1
Add Xenopus synonyms , Nomenclature history


Gene Function: cytokine

Protein Function :
Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-ce...[+]


Interactants: Loading ...

Disease Ontology:
   STOMACH CANCER

OMIM Diseases:
   GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC
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Xenbase Gene ID XB-GENE-481756 XB-GENE-17342546 XB-GENE-865486
Gene Symbol il1b il1b.L il1b.S
Chromosome Chr03 Scaffold409144
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Xl.415
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 7 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine il1b il1b.L il1b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards IL1B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Il1b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR il1b ZFIN Ensembl
chicken
GEISHA IL1B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. [Proc Natl Acad Sci U S A 1984]
Most recent: Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus. [Dev Cell 2018]
View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 0 term 7 terms
PANTHER il1b
KEGG Pathways K04519
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Antibody Il1b Ab1 Il1b Ab1
Affymetrix 1.0 StrEns.1049.1.S1_at Xl.415.1.S1_at
Affymetrix 2.0 Xl2.415.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556