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Summary Expression Gene Literature (53) GO Terms (31) Nucleotides (74) Proteins (40) Interactants (542) Wiki
XB-GENEPAGE-481809
Gene Symbol:
gli2

Gene Name:
GLI family zinc finger 2

Synonyms:
gli4 ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
Has an essential role in the early embryonic patterning of mesoderm and neuroectoderm.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
holoprosencephaly 9 [+]

OMIM:
HOLOPROSENCEPHALY 9; HPE9 [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-481810 XB-GENE-17342592 XB-GENE-6251939
Gene Symbol gli2 gli2.L gli2.S
Chromosome scaffold_498 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100498653
397838
398107
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gli2 gli2.L gli2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GLI2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gli2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gli2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gli2a gli2b ZFIN Ensembl
chicken
GEISHA GLI2 Ensembl
fruit fly
worm
Publications
First Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development., Development 1997  
Most Recent The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation., Cell Commun Signal 2020                
All View All Papers 4 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 6 terms 5 terms
PANTHER gli2
KEGG Pathways K16798 K16798 K16798
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gli2
Antibodies gli2 Ab1 , gli2 Ab2 gli2 Ab1 , gli2 Ab2 gli2 Ab1 , gli2 Ab2
Morpholinos gli2 MO1 , gli2 MO2 gli2 MO1 , gli2 MO2 gli2 MO1 , gli2 MO2
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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