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Summary Expression Gene Literature (72) GO Terms (7) Nucleotides (60) Proteins (22) Interactants (606) Wiki
XB-GENEPAGE- 481991

Gene Symbol: smad3

Gene Name: SMAD family member 3

Synonyms: XSmad3 , XenMLP
Add Xenopus synonyms , Nomenclature history

Gene Function: signal transduction, TGF-beta pathway

Protein Function:


Interactants: YYY

OMIM Disease Associations: LOEYS-DIETZ SYNDROME 3; LDS3
1/4
 
Xenbase Gene ID XB-GENE-481992 XB-GENE-864816 XB-GENE-17345125
Gene Symbol smad3 smad3.L smad3.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.26753 Xl.11953
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 10 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine smad3 smad3.L smad3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu050m05      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMAD3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Smad3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN smad3a smad3b ZFIN Ensembl
chicken
GEISHA SMAD3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. [Nature 1996]
Most recent: Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair. [FASEB J 2016]
View All Papers 14 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 7 terms 0 term
EC
PANTHER smad3
KEGG Pathways K04500 K04500
KOG [TK] TGFbeta receptor signaling protein SMAD and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Smad3 Ab1 , Smad3 Ab2 , Smad2 Ab8 , Smad2 Ab9 Smad3 Ab1 , Smad3 Ab2 , Smad2 Ab8 , Smad2 Ab9
Morpholino smad3 MO1 smad3 MO1 smad3 MO1
Affymetrix 1.0 Str.26753.1.S1_at [+] Xl.11953.1.S1_at
Affymetrix 2.0 Xl2.11953.1.S1_at

Symbol legend[+]

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