Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (335) GO Terms (13) Nucleotides (97) Proteins (51) Interactants (213) Wiki
XB-GENEPAGE-482020
Gene Symbol:
runx2

Gene Name:
RUNX family transcription factor 2

Synonyms:
ccd , aml3 , ccd1 , osf2 , cbfa1 , pea2aa , pebp2a1 , pebp2a2 , pebp2aa , pebp2aa1 , Xlrunx2 , X-runx2 ( Add synonyms , Nomenclature history )

Gene Function:
transcriptional regulator

Protein Function :


InterPro :
Tc1-like DDE dom , Cro/C1-type HTH , Transposase Tc1-like , Homeobox-like sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
cleidocranial dysplasia

OMIM:
CLEIDOCRANIAL DYSPLASIA; CCD [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-482021 XB-GENE-864817 XB-GENE-17334588
Gene Symbol runx2 runx2.L runx2.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100189546
100037059
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine runx2 runx2.L runx2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RUNX2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Runx2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Runx2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR runx2b runx2a ZFIN Ensembl
chicken
GEISHA RUNX2 Ensembl
fruit fly
worm
Publications
First Expression and characterization of a new species of 11 beta-hydroxysteroid dehydrogenase in Xenopus oocytes., Am J Physiol 1993  
Most Recent cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner., J Gen Physiol 2019                
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 6 terms 0 term
PANTHER runx2
KEGG Pathways K09278 K09278
KOG [K] Runt and related transcription factors
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks runx2
Mutants Xtr.runx2emHorb
Morpholinos runx2 MO1 , runx2 MO2 , runx2 MO3 runx2 MO1 , runx2 MO2 , runx2 MO3 runx2 MO1 , runx2 MO2 , runx2 MO3
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list