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Summary Expression Gene Literature (107) GO Terms (2) Nucleotides (63) Proteins (26) Interactants (614) Wiki
XB-GENEPAGE- 482076

Gene Symbol: szl

Gene Name: sizzled

Synonyms: secreted frizzled , xszl , sizzled , frzb3
Add Xenopus synonyms , Nomenclature history


Gene Function: CRD domain wnt inhibitor

Protein Function:


Interactants: Loading ...

OMIM Disease Associations:
1/7
 
Xenbase Gene ID XB-GENE-482077 XB-GENE-482081 XB-GENE-17342129
Gene Symbol szl szl.L szl.S
Chromosome Chr03 chr3L
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.16161 Xl.620 Xl.3606
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 87 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine szl szl.L szl.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM, MalaCards, KEGG Disease, DECIPHER Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN szl ZFIN Ensembl
chicken
GEISHA LOC417741 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Fritz: a secreted frizzled-related protein that inhibits Wnt activity. [Mech Dev 1997]
Most recent: The crystal structure of full-length Sizzled from Xenopus laevis yields insights into Wnt-antagonistic function of secreted Frizzled-related proteins. [J Biol Chem 2017]
View All Papers 33 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 2 terms 0 term
EC
PANTHER szl
KEGG Pathways
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Szl Ab1 Szl Ab1
Morpholino szl MO1 , szl MO2 szl MO1 , szl MO2 szl MO1 , szl MO2
Affymetrix 1.0 Str.16161.1.S1_at Xl.620.1.S1_s_at [+]
Affymetrix 2.0 Xl2.620.1.S1_s_at [+]

Symbol legend[+]

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