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Summary Expression Gene Literature (20) GO Terms (18) Nucleotides (206) Proteins (60) Interactants (637) Wiki
XB-GENEPAGE-482100
Gene Symbol:
spry2

Gene Name:
sprouty RTK signaling antagonist 2

Synonyms:
Xsprouty2 , sprouty2 , sprouty-2 , sprouty 2 , Xtsprouty2 , xspry2 ( Add synonyms , Nomenclature history )

Gene Function:
regulation of signal transduction

Protein Function :


InterPro :
Tc1-like DDE dom , WH-like DNA-bd sf , Transposase Tc1-like , Homeobox-like sf [+]

Interactants:
Loading ...

Diseases: 


OMIM:
IgA NEPHROPATHY, SUSCEPTIBILITY TO, 3; IGAN3

External Links:
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Xenbase Gene ID XB-GENE-482101 XB-GENE-17333940 XB-GENE-864828
Gene Symbol spry2 spry2.L spry2.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 449471
398232
398313
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine spry2 spry2.L spry2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SPRY2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spry2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spry2 Ensembl
zebrafish
ZFIN, AGR spry2 ZFIN Ensembl
chicken
GEISHA SPRY2 Ensembl
fruit fly
worm
Publications
First Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning., Genes Dev 2001                  
Most Recent Sprouty2 regulates positioning of retinal progenitors through suppressing the Ras/Raf/MAPK pathway., Sci Rep 2020                        
All View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 7 terms 7 terms
PANTHER spry2
KEGG Pathways K17383 K17383 K17383
KOG [T] Signal transduction protein Enabled, contains WH1 domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks spry2
Morpholinos (on-target & off-target) spry2 MO1 , spry2 MO2 , spry2 MO3 spry2 MO2 , spry2 MO1 , spry2 MO3 spry2 MO2 , spry2 MO1 , spry2 MO3
ORFs spry2 ORF1 spry2.L ORF1 spry2.S ORF1
Clones Horizon Source BioScience EXRC Horizon EXRC Horizon Source BioScience
Plasmids Addgene Addgene

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