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Summary Expression Gene Literature (18) GO Terms (8) Nucleotides (1045) Proteins (34) Interactants (415) Wiki
XB-GENEPAGE-482184
Gene Symbol:
tubb

Gene Name:
tubulin beta class I

Synonyms:
XLOT , tubulin beta-1 , tubb beta-5 , beta5-tubulin , tubb5 ( Add synonyms , Nomenclature history )

Gene Function:
microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
complex cortical dysplasia with other brain malformations 6

OMIM:
CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 6; CDCBM6 [+]

External Links:
 
Xenbase Gene ID XB-GENE-482185 XB-GENE-864839 XB-GENE-17336360
Gene Symbol tubb tubb.L tubb.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 448742
380418
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tubb tubb.L tubb.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards TUBB OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
Gm9007 Ensembl
rat
zebrafish
chicken
GEISHA TUBB Ensembl
fruit fly
Publications
First Specific inhibition of beta-tubulin synthesis in Xenopus oocytes using anti-sense oligodeoxyribonucleotides., Gene 1988  
Most Recent The Stemness Gene Mex3A Is a Key Regulator of Neuroblast Proliferation During Neurogenesis., Front Cell Dev Biol 2020              
All View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 6 terms 0 term
PANTHER tubb
KEGG Pathways K07375 K07375
KOG [Z] Beta tubulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tubb
Antibodies Tubb Ab1 , Tubb Ab2 Tubb Ab1 , Tubb Ab2 Tubb Ab1
ORFs tubb ORF1 tubb.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info