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Summary Expression Gene Literature (34) GO Terms (11) Nucleotides (37) Proteins (16) Interactants (308) Wiki
XB-GENEPAGE- 482218

Gene Symbol: nkx2-2

Gene Name: NK2 homeobox 2

Synonyms: XeNK-2 , nkx2.2 , Xnkx2.2
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Defines dorsal-ventral domains in developing brain. May play a role in defining positional information along the anterior-posterior (a/p) axis and the dorsal-ventral (d/v) axis of the developing nervou...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/3
 
Xenbase Gene ID XB-GENE-482219 XB-GENE-17336182 XB-GENE-864842
Gene Symbol nkx2-2 nkx2-2.L nkx2-2.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.59933 Xl.664
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 23 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine nkx2-2 nkx2-2.L nkx2-2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NKX2-2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Nkx2-2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN nkx2.2a nkx2.2b ZFIN Ensembl
chicken
GEISHA NKX2-2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: A Xenopus homebox gene defines dorsal-ventral domains in the developing brain. [Development 1993]
Most recent: Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis. [Dev Biol 2017]
View All Papers 6 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 3 terms 4 terms
EC
PANTHER nkx2-2
KEGG Pathways K08029 K08029 K08029
KOG [K] Transcription factor tinman/NKX2-3, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Nkx2-2 Ab1
Affymetrix 1.0 Str.52269.1.S1_at Xl.664.1.S1_at
Affymetrix 2.0 Xl2.664.1.S1_at

Symbol legend[+]

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