gadd45a Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (6)

Nucleotides (215)

Interactants (21)

XB-GENEPAGE-482256

Gene Symbol: gadd45a Gene Name: growth arrest and DNA-damage-inducible, alpha Add Xenopus synonyms Gene Function: 40S ribosomal protein S12 Interactants: gadd45g(2) , aes(1) , cdca8(1) , ddx43(1) , ercc5(1) , eya1(1) , eya2(1) View All	1/4

XB-GENE-482257

XB-GENE-864848

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016151\|Xenopus (Silurana) tropicalis growth arrest and DNA-damage-inducible, alpha (gadd45a), mRNA CGAGAACTGAGGTGAAACTTTCTAGTTCCCAGGAAGAGCCTTGCTGGCCGCAAAATCCACTACAAATCTGCAGCGCTACGGAGCAGTGCAACCCGTACAGCAATATAATATGACTCTGGAGGAGCAGCTGTCTGGGGATCAGAGCATTGGAAAGATGGAGTCAGTGGGAAACGCACTGGAGGAAGTGCTCTGCAAGGCCAAACTGCAGAGGACCATCACTATTGGGGTGTACGAAGCTGCAAAACTTCTCAATGTGGACCCAGACAACGTTGTGCTCTGTTTGTTGGCTACTGACGATACCTACGATCAGGATATCGCTTTACAGATCCACTTCACCCTGATCCAGGCATTTTGCTGTGAGAATGACATCAACATCCTGAGAGTGAGCAACATGAGCCGGCTAGCTGAGATCCTGGGCGGCTCTGACAAGCCTGGGGAACCTGCTGATCTGCATTGTATTCTAATCAACAGCCCACATGAATTACAGGTGAAGGATCCTGCTCTCAAAGAAGTGATTTGTTACTGCAAAGAGAGTCGTTACCTGGACCAGTGGGTGCCTGTGATTAACCTGCCAGAGCGATGATTAAGTATGGCGCACTCCTAATAATTTTAACTGCAGTTTAAGTGAATTAAAAAAAAAAAAATTACTTTCAAGAAGAAAAGTAAAAACACTTTCCAGGACCAGCTTCTGCCATAAAGCAAGGATTTCAATAGCTTGTATACAACATCATGATGGTGGATTTTGGATATGCAGAAGCAGCGCAGAGGTCGCTTAGAAAATGGAGGACTGTTGGTCAAGAAGAACTATGCTGAATTGCACATTGCGCCAATGAGTATCAAGGAAGATGAAACATGAAATTAAGGAGGGTTGGAAAATAGTTCAGGCTGCCATTTGAAATGGGAAATATATATTCTGGCTAATGCATTGGGGTTTTAATTTTGTTCTAAATTCATAAAATGTTAAATTATTGTTTATTTATGCAACTATACTTTAATGTATTCTTTAGGAAACTGGTACACTGACATTTTTATGCATAAAGTTTTTGAGACAAATGAAATGTTTTTAAGTTTTTTTTTTTTTGTTTTTTTTACAATAAAGCTTTTTGAATTGAAAAAAAAAAAAAAAAAA	Refseq >NM_001086068\|Xenopus laevis growth arrest and DNA-damage-inducible, alpha (gadd45a), mRNA AGTCAGCAAGCGAAGAACACGGGACAGTGCTGAGCTATTGTGTATCGGCAATTCGGAGAACTGAGGTGAAACTTTCCAGAGCCCAGAAAGAGCCTCGTTACTAGTGTCAGCGTCCAGTTGATCTGTGCAGAGGAGTGCAACCTGCGCATCGCTATAATATGACTCTGGAGGAGCAGCTGTCTGGGGATCAGAGCATTGGAAAGATGGAATCCGTGGGAAATGCATTGGAGGAAGTACTCCATGAAGCCAAACTGCAGAGGACCATCACCATTGGGGTGTACGAGGCTGCAAAACTCCTTAATGTGGACCCAGACAATGTTGTGCTTTGTCTGTTGGCTACTGATGATAAAGACAATCAGGATGTCGCTTTACAGATTCATTTCACCCTGATCCAGGCATTTTGCTGTGAGAATGACATCAACATCCTGAGAGTGAGCAACATGAGTCGGCTGGCCGAGATCCTGGGCGGCTCTGACAAGCCAGGGGAACCTGCTGATCTGCATTGTATTCTAATCAACAACCCACATGAATTACAGATCAAGGATCCTGCTCTCAAAGAAGTGATTTGTTACTGCAAAGAAAGTCGTTATCTGGACCAATGGGTGCCTGTGATTAACCTGCCAGAGCGATGATCACATACAGCGTACCATTATAATTTAACTGCAGTTTAAATGAAATTTTTAAAAAAAAAAATTACTTTCAAGAAGAAAAGTAAACACTTTTCCAGGACCAGGTTCTGCCATAAAGCAAAGATTTCAATAACTCACATAAAACATCACGAGGGAGGATTTTGGGATATGCAGAAGCCGTGTAGAGGTCACTCATGAAATGGAGGACTGTTGGCCAAAAAGAACCGTGCAGAGCTGTACTTTGCACCAATGAGTATCAAAAAAGATTACCTGAAATTAAGGAGGATTTGAAAATAGTTCAGGCTGCCATATGAAATGGAAAATGTATGTTATGGCAAAGGAATAGGATTTAATTTTGTTCTAGGTTTATAAAATGTTAAATTATTTTGTTTATGCTATTGTTCTTTAATGTATTCTTTAGCAAATTGGTACAATGGCTTTTATGCAGGAAGTTGTTGAGACAAGTGAAATGAAATGTTTTTTAAATTTTATTTTTTTACAATAAAACGTTTGAATTGGCTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016151\|growth arrest and DNA-damage-inducible, alpha [Xenopus (Silurana) tropicalis] MTLEEQLSGDQSIGKMESVGNALEEVLCKAKLQRTITIGVYEAAKLLNVDPDNVVLCLLATDDTYDQDIALQIHFTLIQAFCCENDINILRVSNMSRLAEILGGSDKPGEPADLHCILINSPHELQVKDPALKEVICYCKESRYLDQWVPVINLPER	Refseq >NP_001079537\|growth arrest and DNA-damage-inducible, alpha [Xenopus laevis] MTLEEQLSGDQSIGKMESVGNALEEVLHEAKLQRTITIGVYEAAKLLNVDPDNVVLCLLATDDKDNQDVALQIHFTLIQAFCCENDINILRVSNMSRLAEILGGSDKPGEPADLHCILINNPHELQIKDPALKEVICYCKESRYLDQWVPVINLPER

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.71159
Unigene EST Profile			EST Profile
GEO data			GEO
Images		7 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GADD45A
mouse		MGI	Gadd45a	All(2) Targeted, knock Out(2)
zebrafish		ZFIN ZFIN	gadd45ab gadd45aa	1 Lines(s)

Publications
First:		Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. [Nature 2007]
Most recent:		Gadd45a, Gadd45b and Gadd45g expression during mouse embryonic development. [Gene Expr Patterns 2013]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[J] 40S ribosomal protein S12

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		Str.26626.1.S1_at	Xl.1519.1.S1_at
Affymetrix 2.0			Xl2.29173.1.S1_at [+] Xl2.47781.1.A1_at Xl2.1519.3.S1_at Xl2.1519.3.S1_s_at

Symbol legend[+]