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Summary Expression Gene Literature (261) GO Terms (12) Nucleotides (49) Proteins (21) Interactants (876) Wiki
XB-GENEPAGE-482367

Gene Symbol: sia1

Gene Name: siamois homeodomain 1

Synonyms: Xsia , Siamois , sia ( Add Xenopus synonyms , Nomenclature history )

Gene Function: homeodomain transcription factor

Protein Function :
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFb...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

GEO Series: GSE93195.
1/3
 
Xenbase Gene ID XB-GENE-482368 XB-GENE-864865 XB-GENE-17331825
Gene Symbol sia1 sia1.L sia1.S
Chromosome scaffold_48 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL Swiss-Prot Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine sia1 sia1.L sia1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM, MalaCards, KEGG Disease, DECIPHER Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
fruit fly
worm
WORMBASE
Publications
First Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis., Cell 1995                
Most Recent Non-acylated Wnts Can Promote Signaling., Cell Rep 2019                    
All View All Papers 51 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 11 terms 0 term
PANTHER sia1
KEGG Pathways
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
Dharmacon Dharmacon Dharmacon
Morpholino sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2
Affymetrix 1.0 Str.26882.1.S1_at [+] Xl.18.1.S1_at
Affymetrix 2.0 Xl2.18.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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