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Summary Expression Gene Literature (241) GO Terms (12) Nucleotides (47) Proteins (20) Interactants (749) Wiki
XB-GENEPAGE- 482367

Gene Symbol: sia1

Gene Name: siamois homeodomain 1

Synonyms: Xsia , Siamois , sia
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFb...[+]


Interactants: Loading ...

OMIM Disease Associations:
1/3
 
Xenbase Gene ID XB-GENE-482368 XB-GENE-864865 XB-GENE-17331825
Gene Symbol sia1 sia1.L sia1.S
Chromosome scaffold_48 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.52995 Xl.18
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 41 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine sia1 sia1.L sia1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM, MalaCards, KEGG Disease, DECIPHER Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
fruit fly
worm
WORMBASE
Publications
First: Characterization of a functional angiotensin II receptor in Xenopus laevis heart. [Pharmacology 1994]
Most recent: The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus. [Mech Dev 2017]
View All Papers 50 paper(s) referencing morpholinos 5 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 11 terms 0 term
EC
PANTHER sia1
KEGG Pathways
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2
Affymetrix 1.0 Str.26882.1.S1_at [+] Xl.18.1.S1_at
Affymetrix 2.0 Xl2.18.1.S1_at

Symbol legend[+]

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