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Summary Expression Gene Literature (268) GO Terms (18) Nucleotides (64) Proteins (32) Interactants (885) Wiki
XB-GENEPAGE-482367
Gene Symbol:
sia1

Gene Name:
siamois homeodomain 1

Synonyms:
Xsia , Siamois , sia ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Essential for Wnt/beta-catenin-mediated formation of the Spemann organizer and for induction of the organizer precursor, the Nieuwkoop center. Acts as a transcriptional activator, cooperating with TGFb...[+]



Interactants:
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Diseases: 


External Links:
GEO Series :
GSE93195.
1/3
 
Xenbase Gene ID XB-GENE-482368 XB-GENE-864865 XB-GENE-17331825
Gene Symbol sia1 sia1.L sia1.S
Chromosome scaffold_48 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100038038
378613
108703521
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine sia1 sia1.L sia1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
Protein Atlas
mouse
rat
zebrafish
chicken
fruit fly
worm
Publications
First Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis., Cell 1995                
Most Recent Natural size variation among embryos leads to the corresponding scaling in gene expression., Dev Biol 2020                      
All View All Papers 52 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 10 terms 0 term
PANTHER sia1
KEGG Pathways
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sia1
Morpholinos sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2 sia1 MO1 , sia1 MO2
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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