Gene Symbol: tdgf1.3 [provisional] Gene Name: teratocarcinoma-derived growth factor 1, member 3 [provisional] Synonyms: Cripto-1, cr1, xcr1, cripto, frl1, frl-1, tdgf1 Add Xenopus synonyms Gene Function: EGF-like growth factor Interactants: nodal(23) , egf(15) , ptpn11(15) , tgfb1(9) , acvr1b(8) , chrd(7) , smad2(7) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001078927|Xenopus (Silurana) tropicalis cripto, FRL-1, cryptic family 1 (cfc1), mRNA GCAACTAAGCAGAGGCTAATTTAGTTCACTTGGTCTGTGGACTGACCACTTTACCTGGCTTTAGCTACAGATACATTAATTAAGAACTATAAGTGGGAAACTAGGGCCTTTGCAGACAACAATGCAGCTTTTAAGATTTCTTGCCATCCTTGTTTTCTCTGCTAAATATTTTATCAAGCATTGCAAAGGTGAATCCTGCGTAGGACTGTACTGTAATGATACCGGTTTATCGCTGGCAATTAAGAGCAACACAATCCATCAGATCTTGCAGGATACAATAAATGCCACACATGGAAAGAGTCCAGAAAAATCTGCTAAGACCTTGCCCTTCTTGGGTATCACAGACAGCAAGAAGTTAAACAAAAAATGCTGTCAGAATGGAGGCACTTGTTTCTTGGGGACTTTTTGCATCTGCCCTAAGCAATTTACTGGTCGGCACTGTGAACATGAAAGGCGCCCAGCAAGCTGCGCCGGTGTTCCCCATGGAGACTGGATCCGTCAGGGCTGCTTGCTGTGTCGATGTGTGTCTGGTGTCCTGCACTGCTTTACTCCTGAGTCTGAGGACTGTGGTCCAGTGCATGAAAAAAATATGAGATCGGGTGTCCCAAGAACGCAACTCAGTTTATTCATCTATTACTTATTTATTGCAAACTTGTTTTATCACATAGTTTGGCATTTGAATATTGGACTTTAGCTGAGTAACTAGAGTCTGCTAGTTCAGTCCAGATCAGGCTTCTGTTTCTATACTGCACTTTTAATTGCTAAACCCATTTTGCCAGGATTATGCTTAGAATTATATTGCTACCCCCAGAATCCGGAAAATATTCACAAGCTATAGAATGTCTTATATTCAGTGCTGATGTCTAGGGGTCAGAATGGGTTTGCAGTACTTCCGAGCACTGGAGTTGGTTTAAGATATAGCTGCTGGGCTCTTGCTCCTTGCTGTAAATTTCAGATCAGGGACTTAGCCTTATACTTACCCAGTGCATTCTGTATATATGTAAATTTTATTAATTTATTAATCAGACAAGTTGTACCTTAACAATGTCCTTCACTCACTTTTTTTTTTTATATATATATATCACAATGATTTTATTTTTTACTTTTTTCTTAACTGACAAAGAGAAAAAAATCTCTAGGAACATAATATACAGATATTGTCCTACTACATAAATGTCACATTGCATGTTATGGTACTTGTATGTTTGTCTTGACCTACAACAATGTGTCCCTAGCCATGAAACCCTAGAGATTTGTTTTTATGTGAAACCAAATGGGCCACAATAGTGCTTAAACAAAAAAAAATGTAAAATTGGTTGTTTAGAAGATGAGTCAATGCATCCTATAATTTCAGTTTTAGGGTACAGGCATTTAGTTATAGGTCAGGAGATAATACAATTACCCGTGTTGCTGTACCTATGTACTTACAGTTTGTCCACTTGATGTTTGCAATGAAACATTAAATACGTAAAAGAAAAAAAAAAAAAAAAAA	Refseq >NM_001088462|Xenopus laevis teratocarcinoma-derived growth factor 1 (tdgf1), mRNA CCGACCGTTACACCTGGTTTTTGCTAAGGACACATTCAATACAAGAACTAAAAGTGGGAAACTGGGGCCTTTGCAGAAAACAATGCAGTTTTTAAGATTTCTTGCCATCCTTATTTTCTCTGCTAAACATTTTATCAAGCATTGCAAAGGTGAAACTTGCATGGGACTGAACTGTAATGACCCAAGGTTATTGGAGGCAATTAAGAGCAACACAATCAATCAGCTCTTGCATGATACAATTAATGCCACCCATGGAAAGAGTCCACCAAAATCCACTAAAACCTTGCCCTTCTTGGGTATCACAGACAGTAAGAAATTGAATAGAAAATGCTGTCAGAATGGAGGCACTTGTTTCTTGGGGACCTTTTGCATCTGCCCTAAGCAATTTACTGGTCGGCACTGTGAACATGAAAGGAGGCCAGCAAGCTGCTCCGGTGTTCCCCATGGAGACTGGATCCGTCAGGGCTGCTTGCTGTGTAGATGTGTGTCTGGTGTCCTACACTGCTTCAAGCCCGAGTCTGAGGACTGTGATGTTGTGCATGAAAAAAACATGAGATCGGGGGTCCCGAGAATGCAGCTCAGCTTAATCATCTATTGCTTCCTTACTGCAAACTTGTTTTACCACATAGTTTGGCATCTGAATATTGGACTTTAACAGAGTAACTTGAGTCTGCCAGTCAGGTTCAGATTGCAGACGTCTGTGTCTACACTGCACTTTCAATTTGTGAACCCATTTTGCCAGGATTATGCTTGAAGTATATGGCTATCTTCCACCCCTGGAATCCTGGAAAATATGCAGAAACTATACAATGCCTTATTTCTATTGGTTGTTTCATAAAATAACTTTTTTTATAGGATGATGTGTATAGTGGCCAGAATGGGTTTACAGTACTTCCAAGCACTGGCGTTGGTTCAAAATAGCTACTGGGTTCTTGCTCTTTGCTGCATGTTGAGATCAGGAAGCTAGTCTTATACTTACCCAGTGCATTCTGTATATATGTAAATTTTATTAACTTATTAGACACGTTGTACATTAACAGCATCCTTCACAAACTTTTATTTTTTTTTAATTTTTTTATTAATTGACAAAGAGAACAAAGTATCTAGGAACATTTTACAAATATTGTCCTACTACATTGCATGTTGTGGTTCTTGTTTGTATGTTTGTCCTGATCTTCTACAATGTATCCCTAGCCATAAAACGATTTTGTGAGTGTGTGTGTGTGACTGCATCCCATTTTATTCATTATGCAAACACTTTGCAAATGATTGTGCAGCAATGTAAGTGCTAGCCTGTGGTCAACAGTGCTGAATGTAAATCTTGGAGCGGTGATATCAGCATGCTTATGGAGGCTCAATAACCTTGGTCTTGCCCCTTTAAATTCTATTTTTCTACGGGCAAGTAAATCTAAACTGGTAAAGTACCTTCTTTTAAGGAAATGAATCACTGAATGTTATAATTCCAGTTTCAGGCCACAGACAATTAATGACAGCTCAGGGAATAATACAATTGCCCATGTTTGATGCACCTAATGTACTGTATGTATTACAGGGTGTCTGCTTGATGTTTGCAATGAAGACATTAAATACTGTACCTAAAAGAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001072395|cripto, FRL-1, cryptic family 1 [Xenopus (Silurana) tropicalis] MQLLRFLAILVFSAKYFIKHCKGESCVGLYCNDTGLSLAIKSNTIHQILQDTINATHGKSPEKSAKTLPFLGITDSKKLNKKCCQNGGTCFLGTFCICPKQFTGRHCEHERRPASCAGVPHGDWIRQGCLLCRCVSGVLHCFTPESEDCGPVHEKNMRSGVPRTQLSLFIYYLFIANLFYHIVWHLNIGL	Refseq >NP_001081931|teratocarcinoma-derived growth factor 1 precursor [Xenopus laevis] MQFLRFLAILIFSAKHFIKHCKGETCMGLNCNDPRLLEAIKSNTINQLLHDTINATHGKSPPKSTKTLPFLGITDSKKLNRKCCQNGGTCFLGTFCICPKQFTGRHCEHERRPASCSGVPHGDWIRQGCLLCRCVSGVLHCFKPESEDCDVVHEKNMRSGVPRMQLSLIIYCFLTANLFYHIVWHLNIGL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.6258	Xl.1289
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TDGF1
mouse		MGI	Tdgf1	All(8) Targeted, knock Out(2) Targeted, other(5)
zebrafish

Publications
First:		Translation of the human C3b/C4b receptor mRNA in a cell-free system and by Xenopus oocytes. [Biochemistry 1989]
Most recent:		Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/β-catenin signaling and competence provider for Brachyury induction. [Stem Cells Dev 2011]
		View All Papers 6 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[T] Fibrillins and related proteins containing Ca2+-binding EGF-like domains

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6258.1.S1_at	Xl.1289.1.S1_at
Affymetrix 2.0			Xl2.1289.1.S1_at

Symbol legend[+]

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