lhx1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (131)

Nucleotides (113)

Interactants (425)

XB-GENEPAGE-482481

Gene Symbol: lhx1 Gene Name: LIM homeobox 1 Synonyms: Xlim1, Xlim-1, Lim1, lim-1, lim1 Add Xenopus synonyms Gene Function: LIM and homeodomain containing transcription factor Interactants: gsc(37) , t(30) , pax8(23) , chrd(21) , pax2(20) , otx2(19) , cer1(16) View All	1/6

XB-GENE-482482

XB-GENE-856460

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001100228\|Xenopus (Silurana) tropicalis LIM homeobox 1 (lhx1), mRNA GACAGTTCGGATGGGAAGAGCCAGTCTGTGGAGCAAACCTGTAGGATCGCCAGCTCCAGTGCCAGCTTCTCAGCAACCTGCACCACAGCCAAGGGATCGCTCTCTGCATTGGCACCGTAGATGCTCACGGGGGATTCCTTCATTCATCGACTTTGTTCAGCAGCTAGTGGGATTTGGACAATAAAGCCAGGGGCAGAAGTTGTTGATGGGCTAGGGGACTTCCTTGGTGACGTTAAGTGAGAACGGGCAAAGGAATCAGCCCCCGGGATACCAAGAGGAGTGGGAAGAAAAGGAAAATTATTTAACTGCAAGCCGAACCAACGGCCCGAGGTGTGTTTGTGGAGCCTGTCCGTGGCGCTGGACGTGATGCCGGGCAACCTAAATCCCCTTGGCTTGTAATTTCTATAGCCAAACAGATGCACTTTCAGCATTGACTGCGCTACCTCAGAGCCAGAAGGCAACTGATCGCCCCACATCTCTGCCCTCTCCTACCTCCTGCTACCTTGGCTTGGGGATCTCCATCAGCTCCGTCTGCTTGTCTTTCTGGACCATAGTGTCTGCCTTCTGTCCTCCTAACCCGTCCCCTTCCTTTAAAATCCCAAATAACCAAAGACAATGGTTCACTGTGCTGGATGCGAAAGGCCCATTCTGGATCGTTTCTTGTTGAATGTGCTGGACAGGGCTTGGCATGTGAAATGCGTGCAGTGCTGCGAGTGTAAGTGCAATCTGACCGAGAAATGCTTCTCCAGGGAGGGCAAGCTCTACTGCAAAAACGACTTCTTCAGGCGCTTTGGTACCAAGTGTGCGGGCTGTGCCCAGGGGATCTCCCCCAGTGACCTAGTCAGGAGGGCAAGGAGCAAAGTGTTTCACTTGAACTGTTTCACCTGTATGATGTGTAACAAACAGCTCTCCACTGGAGAGGAACTTTATATCATCGATGAGAATAAGTTTGTCTGCAAAGAAGATTACTTAAACAACAACAACAACAACAACAACGCTGCCAAAGAAAACAGCTTTATCTCAGTAACAGGCAGTGACCCCAGTTTATCTCCTGAATCTCAAGACCCGCTGCAAGATGACGCTAAAGACTCTGAAAGTGCCAATATCTCTGATAAGGAGGCTGGGGTTAATGAAAACGACGACCAAAACCTTGGGGCGAAAAGAAGGGGACCTAGGACCACTATCAAAGCCAAACAGCTGGAGACCCTGAAAGCAGCTTTTGCAGCTACACCAAAACCGACCCGGCACATAAGGGAGCAGCTGGCACAGGAGACTGGTCTCAACATGCGAGTCATCCAGGTCTGGTTCCAGAACCGACGATCCAAAGAGAGAAGAATGAAACAGCTGAGCGCTCTGGGGGCCCGCAGACACGCCTTCTTCCGCAGCCCCCGAAGGATGAGGCCGCTGGTGGACAGGTTAGAGCCGGGGGAACTCATCCCCAATGGACCCTTCTCCTTCTATGGAGATTATCAGAGTGAGTATTATGGCCCTGGCAGCAACTATGACTTTTTCCCACAAGGACCCCCATCATCTCAAGCTCAGACTCCTGTAGATTTGCCATTTGTTCCTTCTTCTGGGCCTGCAGGAACTCCACTTGGTGCAATGGATCACCCAATCCCTGGACACCACCCATCTAGTGACGCTCAGAGGTTTACTGACATAATGTCCCACCCACCAGGAGACTCTCCAAGCCCAGAGCCCAATCTACCAGGTTCCATGCACTCTATGTCTGCAGAAGTGTTTGGTCAAAGTCCCCCCTTTTCTTCTCTATCGGTCAATGGAGCAGCAGGTTATGGCAACCATTTGTCACACCCGCCAGAAATGAACGAAACTGCAGTGTGGTAGCCTAAGTTGGACAAAAACAGAAACAAAAAATCAGAAAGGACTGGGTGCAATGGGCTACCATGTCAACGTTTCCTATGAAAATAACGTGGTGTACAGAACTGGTAAATAAAATTATATTCTGTCCTAAAGGTGTGTACAGTTTTGGATGGAAAAAAAATAATTTGCAAGAATATGCCATAATATGGATTCAAAGAAAAAAATATTTTCTAAGATGACAGAAAAATCAAACTGGTGACGCTGTAAAGTAGAGTTTTGTCATGCTAGGGGATGGAAAAGAATAGCCTGGTAGGTGGTACACAGGACACAATATAAATCTGCTTTCATTGTACACACAGTACACCTAAGTGCAAGTGATAATCTTGAAGGACTCCATAGGAAAAAAAATACCTTATCAAGAATTGCCTAGAATGTTGAGTCTGTCTAGAATGTTGAGCTTTCTCTTCCTTGGAGAAATGTACTGTAGCCAGACTGTTTTAGCTTCAGACACGCACCTGTATATTCAGGTGCGACACAACATTTGCCAAAATAACAAAATACAACAATGTAAACCCCTCAGCATCAACTATTCTACCTTCACAAAGCTACTCACACGAAAAAATAAAATCCTCATTATGAAGGTCTGTTGGAAGACCTGGAAGGAGACTTGAAACAAAAAATAGATTCTACCTTCACTAACAATGAAATAAAATGACTATGGAACTATAAGCAGTCAACTGTTTACGTCTGACGTCAAATTCAGGAGCCTAATGTTTTAGTAATAATCCTGTTTTAGAAACCTCTTTGTTCAAAAAAAAAAAAAAAAAA	Refseq >NM_001090659\|Xenopus laevis LIM homeobox 1 (lhx1), mRNA TCTAGACCACAGTGTCTGCCTTCTATTCTCCTAATCCGCCCATTCCTCTAAAATCCCAAATAACCAAAGGCAATGGTTCACTGTGCTGGATGCGAAAGGCCCATTCTGGACCGTTTCTTGTTGAATGTGCTGGACAGGGCTTGGCATGTGAAATGCGTGCAGTGCTGTGAGTGTAAGTGCAACCTGACCGAGAAATGCTTCTCCAGGGAGGGCAAGCTCTACTGTAAAAACGACTTCTTCAGGCGCTTTGGTACCAAGTGTGCGGGCTGTGCCCAGGGGATCTCCCCCAGTGACCTAGTCAGGAGGGCAAGGAGCAAAGTGTTCCACTTGAACTGTTTCACCTGCATGATGTGTAACAAACAGCTCTCCACTGGAGAGGAACTTTATATAATCGATGAGAACAAGTTCGTCTGCAAAGAAGATTACTTAAACAACAACAACGCTGCCAAAGAAAACAGCTTTATCTCAGTAACAGGCAGTGACCCCAGTTTATCTCCTGAATCTCAAGACCCGTTGCAAGATGACGCTAAAGACTCTGAAAGTGCCAATGTCTCTGATAAGGAGGCTGGGATTAATGAAAACGACGACCAAAACCTTGGGGCGAAAAGAAGGGGACCTAGGACCACTATCAAAGCCAAACAGTTGGAGACGCTGAAAGCAGCATTTGCAGCTACACCAAAACCGACCCGACACATAAGGGAGCAGCTGGCACAGGAGACTGGTCTCAACATGCGAGTAATCCAGGTCTGGTTCCAGAACCGACGATCCAAAGAGAGAAGAATGAAACAGCTGAGCGCTCTGGGAGCCCGGAGACACGCCTTCTTCCGCAGCCCCCGAAGGATGAGACCACTGGTGGACAGATTAGAGCCGGGAGAACTCATCCCCAATGGGCCCTTCGCCTTCTATGGAGATTATCAGAGTGAATATTATGGCCCTGGCAGCAACTATGACTTTTTCCCACAAGGACCCCCATCGTCTCAAGCTCAGACTCCTGTAGATTTGCCATTTGTACCTTCCTCTGTGCCCGCAGGAACTCCCCTTGGTGCAATGGATCACCCGATCCCCGGACACCACCCATCTAGTGACGCTCAGAGGTTTACTGACATAATGTCCCACCCACCAGGAGACTCTCCAAGCCCAGAGCCCAATCTACCAGGTTCCATGCACTCTATGTCTGCAGAAGTGTTTGGACAAAGTCCCCCCTTTTCTTCTCTATCAGTCAATGGAGGTTATGGCAACCATTTGTCACACCCACCAGAAATGAACGAAACGGCAGTGTGGTAGCCTAAGCTGGACAAAAACAGAAAAAAAATCAGAAAGGACTGGGTACAATGGGCTACCATGTAAAGGTTTCCTATGAAAATAAC
Protein		Refseq >NP_001093698\|LIM homeobox 1 [Xenopus (Silurana) tropicalis] MVHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNNNNNNNAAKENSFISVTGSDPSLSPESQDPLQDDAKDSESANISDKEAGVNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFSFYGDYQSEYYGPGSNYDFFPQGPPSSQAQTPVDLPFVPSSGPAGTPLGAMDHPIPGHHPSSDAQRFTDIMSHPPGDSPSPEPNLPGSMHSMSAEVFGQSPPFSSLSVNGAAGYGNHLSHPPEMNETAVW	Refseq >NP_001084128\|LIM/homeobox protein Lhx1 [Xenopus laevis] MVHCAGCERPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLNNNNAAKENSFISVTGSDPSLSPESQDPLQDDAKDSESANVSDKEAGINENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLVDRLEPGELIPNGPFAFYGDYQSEYYGPGSNYDFFPQGPPSSQAQTPVDLPFVPSSVPAGTPLGAMDHPIPGHHPSSDAQRFTDIMSHPPGDSPSPEPNLPGSMHSMSAEVFGQSPPFSSLSVNGGYGNHLSHPPEMNETAVW UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.12750	Xl.32655 [+] Xl.81258
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		82 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tgas028k15

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	LHX1
mouse		MGI	Lhx1	All(9) Targeted, knock Out(2) Targeted, other(7)
zebrafish		ZFIN ZFIN	lhx1a lhx1b	1 Lines(s)

Publications
First:		The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. [Genes Dev 1992]
Most recent:		Characterization of the hypothalamus of Xenopus laevis during development. I. The alar regions. [J Comp Neurol 2013]
		View All Papers 29 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity zinc ion binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[K] Transcription factor LIM3, contains LIM and HOX domains

Reagents		tropicalis	laevis
Clones			EXRC - 4 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.4659.1.S1_s_at [+] Str.12750.2.S1_s_at Str.12750.1.A1_at	Xl.1226.1.S1_at
Affymetrix 2.0			Xl2.54421.1.A1_at [+] Xl2.54421.2.A1_at Xl2.32655.1.S1_at

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