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Summary Expression Gene Literature (197) GO Terms (56) Nucleotides (114) Proteins (26) Interactants (1726) Wiki
XB-GENEPAGE-482481

Gene Symbol: lhx1

Gene Name: LIM homeobox 1

Synonyms: Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1 ( Add synonyms , Nomenclature history )

Gene Function: LIM and homeodomain containing transcription factor

Protein Function :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

1/6
 
Xenbase Gene ID XB-GENE-482482 XB-GENE-856460 XB-GENE-17343236
Gene Symbol lhx1 lhx1.L lhx1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine lhx1 lhx1.L lhx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas028k15      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LHX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lhx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR lhx1a lhx1b ZFIN Ensembl
chicken
GEISHA LHX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos., Genes Dev 1992                
Most Recent Mechanistic insights from the LHX1-driven molecular network in building the embryonic head., Dev Growth Differ 2019  
All View All Papers 43 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 51 terms 0 term
PANTHER lhx1
KEGG Pathways K09372 K09372
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Lhx1 Ab1 Lhx1 Ab1
Morpholino lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2
Affymetrix 1.0 StrJgi.4659.1.S1_s_at [+] Xl.1226.1.S1_at
Affymetrix 2.0 Xl2.54421.1.A1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.4


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