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XB-GENEPAGE-
482481
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Gene Symbol: lhx1
Gene Name: LIM homeobox 1 Synonyms: Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1 Add Xenopus synonyms , Nomenclature history Gene Function: LIM and homeodomain containing transcription factor Protein Function  :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]
Interactants: Loading ... 
Disease Ontology Associations: OMIM Disease Associations: LIM HOMEOBOX GENE 1; LHX1 |
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1/8 | Xenbase Gene ID | XB-GENE-482482 | XB-GENE-856460 | XB-GENE-17343236 | ||||
| Gene Symbol | lhx1 | lhx1.L | lhx1.S | ||||
| Chromosome | Chr02 | chr2L | chr2S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.12750 | Xl.32655 [+] | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 117 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | lhx1 | lhx1.L | lhx1.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | tgas028k15 | ||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: |
The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. [Genes Dev 1992]
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| Most recent: |
ADMP controls the size of Spemann''s organizer through a network of self-regulating expansion-restriction signals. [BMC Biol 2018]
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| View All Papers 41 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontologies | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 5 terms | 67 terms | 0 term | ||||
| PANTHER | lhx1 | ||||||
| KEGG Pathways | K09372 | K09372 | |||||
| KOG |
[K] Transcription factor LIM3, contains LIM and HOX domains
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 4 clone(s) | ||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Antibody | Lhx1 Ab1 | Lhx1 Ab1 | |||||
| Morpholino | lhx1 MO1 , lhx1 MO2 | lhx1 MO1 , lhx1 MO2 | lhx1 MO1 , lhx1 MO2 | ||||
| Affymetrix 1.0 | StrJgi.4659.1.S1_s_at [+] | Xl.1226.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.54421.1.A1_at [+] | ||||||
Symbol legend[+]
