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Summary Expression Gene Literature (1095) GO Terms (76) Nucleotides (135) Proteins (47) Interactants (1760) Wiki
XB-GENEPAGE-482481
Gene Symbol:
lhx1

Gene Name:
LIM homeobox 1

Synonyms:
Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1 ( Add synonyms , Nomenclature history )

Gene Function:
LIM and homeodomain containing transcription factor

Protein Function :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]


InterPro :
ENaC , UDP glucos trans , Znf LIM , Homeobox dom [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-482482 XB-GENE-856460 XB-GENE-17343236
Gene Symbol lhx1 lhx1.L lhx1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100101708
399323
108709506
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lhx1 lhx1.L lhx1.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen tgas028k15      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LHX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lhx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lhx1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR lhx1a lhx1b ZFIN Ensembl
chicken
GEISHA LHX1 Ensembl
fruit fly
worm
Publications
First The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos., Genes Dev 1992                
Most Recent In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces., Fluids Barriers CNS 2020                    
All View All Papers 43 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 68 terms 6 terms
PANTHER lhx1
KEGG Pathways K09372 K09372
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lhx1
Antibodies Lhx1 Ab1 Lhx1 Ab1
Morpholinos lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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