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Summary Expression Gene Literature (181) GO Terms (68) Nucleotides (118) Proteins (27) Interactants (1486) Wiki
XB-GENEPAGE- 482481

Gene Symbol: lhx1

Gene Name: LIM homeobox 1

Synonyms: Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1
Add Xenopus synonyms , Nomenclature history


Gene Function: LIM and homeodomain containing transcription factor

Protein Function :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: LIM HOMEOBOX GENE 1; LHX1
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Xenbase Gene ID XB-GENE-482482 XB-GENE-856460 XB-GENE-17343236
Gene Symbol lhx1 lhx1.L lhx1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.12750 Xl.32655 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 117 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lhx1 lhx1.L lhx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas028k15      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LHX1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lhx1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR lhx1a lhx1b ZFIN Ensembl
chicken
GEISHA LHX1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. [Genes Dev 1992]
Most recent: ADMP controls the size of Spemann''s organizer through a network of self-regulating expansion-restriction signals. [BMC Biol 2018]
View All Papers 41 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 67 terms 0 term
PANTHER lhx1
KEGG Pathways K09372 K09372
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 4 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Lhx1 Ab1 Lhx1 Ab1
Morpholino lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2
Affymetrix 1.0 StrJgi.4659.1.S1_s_at [+] Xl.1226.1.S1_at
Affymetrix 2.0 Xl2.54421.1.A1_at [+]

Symbol legend[+]
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