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Summary Expression Gene Literature (198) GO Terms (75) Nucleotides (133) Proteins (44) Interactants (1732) Wiki
Gene Symbol:

Gene Name:
LIM homeobox 1

Xlim1 , Xlim-1 , Lim1 , lim-1 , lim1 ( Add synonyms , Nomenclature history )

Gene Function:
LIM and homeodomain containing transcription factor

Protein Function :
Involved in the establishment of the body plan via the Spemann organizer during gastrulation. Transcriptional activator required to induce organizer gene expression downstream of siamois. Promotes head...[+]

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External Links:
Xenbase Gene ID XB-GENE-482482 XB-GENE-856460 XB-GENE-17343236
Gene Symbol lhx1 lhx1.L lhx1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100101708
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq Swiss-Prot Uniprot GO NCBI Protein
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine lhx1 lhx1.L lhx1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas028k15      
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards LHX1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Lhx1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Lhx1 Ensembl
ZFIN, AGR ZFIN, AGR lhx1a lhx1b ZFIN Ensembl
fruit fly
First The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos., Genes Dev 1992                
Most Recent Amphibian thalamic nuclear organization during larval development and in the adult frog Xenopus laevis: Genoarchitecture and hodological analysis., J Comp Neurol 2020  
All View All Papers 43 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 66 terms 4 terms
KEGG Pathways K09372 K09372
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks lhx1
Antibodies Lhx1 Ab1 Lhx1 Ab1
Morpholinos lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2 lhx1 MO1 , lhx1 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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