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XB-GENEPAGE-482653
Gene Symbol:
zic2
Gene Name: Zic family member 2
Synonyms:
Zinc finger protein of the cerebellum 2
,
xzic2
,
hpe5
,
zic2-a
,
zic2-b
( Gene Function: zinc finger, C2H2 type Protein Function
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Transcriptional repressor that inhibits neurogenesis and induces neural and neural crest differentiation. Regulates anteroposterior patterning in early development by inhibiting expression of the nodal...[+]
Interactants:
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Diseases: Disease Ontology:
holoprosencephaly 5
OMIM:
HOLOPROSENCEPHALY 5; HPE5
External Links:
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Xenbase Gene ID
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XB-GENE-482654 | XB-GENE-482658 | XB-GENE-6251643 | |||||
Gene Symbol | zic2 | zic2.L | zic2.S | Chromosome | Chr2 | chr2L | chr2S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
549779
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397704
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379115
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | zic2 | zic2.L | zic2.S | |||||
Orthology ![]() |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Gli/Zic factors pattern the neural plate by defining domains of cell differentiation., Nature 1998 |
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Most Recent |
Mcrs1 interacts with Six1 to influence early craniofacial and otic development., Dev Biol 2020 ![]() |
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All | View All Papers 15 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 25 terms | 16 terms | 16 terms | |||||
PANTHER | zic2 | |||||||
KEGG Pathways | K06235 | K06235 | K06235 | |||||
KOG |
[R] FOG: Zn-finger
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | zic2 | |||||||
Morpholinos | zic2 MO2 | zic2 MO1 , zic2 MO2 , zic2 MO3 , zic2 MO4 | zic2 MO1 , zic2 MO2 , zic2 MO3 | |||||
ORFs | zic2.L ORF1 | zic2.S ORF1 | ||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



