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Summary Expression Gene Literature (150) GO Terms (16) Nucleotides (158) Proteins (49) Interactants (1687) Wiki
XB-GENEPAGE- 482739

Gene Symbol: pax3

Gene Name: paired box 3

Synonyms: pax-3 , Waardenburg syndrome 1 , xpax3 , pax3-a , pax3-b , ws1 , cdhs , hup2
Add Xenopus synonyms , Nomenclature history

Gene Function: paired box transcription factor with homeodomain

Protein Function :
Probable transcription factor. Promotes both hatching gland and neural crest cell fates, two of the cell populations that arise from the neural plate border. Acts downstream of msx1 to induce the neura...[+]


Interactants: Loading ...

Disease Ontology Associations: WAARDENBURG SYNDROME TYPE 1 [+]

OMIM Disease Associations: PAIRED BOX GENE 3; PAX3 [+]
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Xenbase Gene ID XB-GENE-482740 XB-GENE-6252072 XB-GENE-482744
Gene Symbol pax3 pax3.L pax3.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.44149 Xl.54870 Xl.49495
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 218 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine pax3 pax3.L pax3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PAX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pax3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR pax3a pax3b ZFIN Ensembl
chicken
GEISHA PAX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities. [Development 1994]
Most recent: Characterization of Pax3 and Sox10 transgenic Xenopus laevis embryos as tools to study neural crest development. [Dev Biol 2018]
View All Papers 50 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 15 terms 15 terms
PANTHER pax3
KEGG Pathways K09381 K09381 K09381
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s) EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Pax3 Ab1 Pax3 Ab1 Pax3 Ab1
Transgene Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP) Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP) Tg(pax3:eGFP) , Tg(pax3:Katushka;cryga:Venus,GFP)
Morpholino pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4 pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4 pax3 MO1 , pax3 MO2 , pax3 MO3 , pax3 MO4
ORF pax3.L ORF1 pax3.S ORF1
Affymetrix 1.0 Str.11142.1.S1_a_at [+] Xl.15871.1.S1_at [+] Xl.25932.2.A1_s_at
Affymetrix 2.0 Xl2Affx.25.1.S1_at [+] Xl2.49495.3.S1_x_at [+]

Symbol legend[+]
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