cdk1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (690)

Nucleotides (361)

Interactants (343)

XB-GENEPAGE-482749

Gene Symbol: cdk1 Gene Name: cyclin-dependent kinase 1 Synonyms: p34cdc2, cell division control protein 2 homolog, cdc-2, xcdc2, cdc2, cdc28a, PSTAIR, cdc2x1.1 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: pold1(448) , ccnb1.2(285) , mapk1(117) , cdc25c(104) , cdk2(85) , rasgrf1(82) , mos(68) View All

XB-GENE-482750

XB-GENE-482754

XB-GENE-6254942

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_203577\|Xenopus (Silurana) tropicalis cyclin-dependent kinase 1 (cdk1), mRNA GGGGGAAAGGCCTCTTGGGCTCTGGGAGTTAAACGGGGGGCTTTGTTCTGCCGGAGGGTTTGCTGGGAATCCAGCCTTGAGGAACCAGCCATGGACGAGTACACTAAAATAGAAAAGATCGGAGAGGGCACATACGGGGTTGTGTACAAGGGTCGCCATAAAGCAACAGGCCAGGTGGTTGCAATGAAGAAAATTCGGTTGGAAAACGAAGAGGAGGGCGTCCCAAGCACAGCGATTAGAGAAATATCACTACTGAAAGAACTTCAGCACCCCAACATAGTTTGCCTTCTAGATGTCCTGATGCAAGACTCAAGGTTGTACCTCATCTTTGAGTTTCTCTCCATGGATCTGAAGAAGTATTTAGACTCAATACCCAGCGGCCAGTATATAGATACAATGCTTGTTAAGAGTTACCTCTACCAGATCCTACAAGGGATTGTATTTTGCCACTCCAGAAGAGTGTTACACAGGGATCTGAAGCCTCAAAACCTGCTGATCGACAGCAAAGGAGTGATAAAGTTGGCAGATTTTGGCCTTGCCAGAGCTTTTGGCATTCCGGTTCGGGTTTACACACACGAGGTAGTGACGTTATGGTACAGAGCCCCAGAAGTGCTGTTGGGGTCAGTCCGATATTCCACACCGGTCGACGTATGGAGCATAGGAACCATTTTTGCTGAGATTGCCACAAAGAAACCCCTCTTCCACGGCGACTCTGAAATTGACCAGCTCTTCAGGATATTCAGAGCTCTGGGAACGCCCAACAATGAAGTGTGGCCTGAAGTGGAGTCTTTACAAGATTACAAGAACACATTCCCCAAATGGAAAGGCGGAAATCTGTCGGCGAATGTGAAAAATATCGATAAGGATGGGCTGGACCTGCTGTCTAAAATGCTAATCTATGATCCCGCCAAGAGAATTTCTGCGCGTAAAGCGTTGCTGCACCCCTACTTTGATGACTTGGATAAGTCCAGCCTTCCTGCCAATCAGATTAGAAATTAACACACTGAGCGTCTCTTCTCTTGGGTTTCTGGGTGGGAATCTGATGTAAATCACTTTCGTTTTTTTTACTGTCTGTACGTTGATGTATATGTGTGTATGTGTCTCGGCGCCCGAAGTACTTACCTTAAAGCACCACACTCTAAATGTAAATATGGACTGACCAAACCTGTGTATAAATGCATTTCCCACACAGACATTTCATTTCCAATAAAGCTTTATTATATATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087085\|Xenopus laevis cyclin-dependent kinase 1 (cdk1-a), mRNA GCAAGTTGCCGAGTTTAGCAGGAAGAAGCGGACGGCGAGGGGGAATCCAGCCTTGGGAAACAGTCATGGACGAGTACACTAAAATAGAAAAGATCGGAGAGGGCACATATGGGGTTGTGTACAAAGGTCGTCACAAAGCAACTGGCCAGGTTGTTGCAATGAAGAAAATTCGATTGGAAAACGAAGAGGAAGGTGTCCCAAGTACAGCAATCCGAGAAATATCACTACTTAAAGAGCTTCAGCACCCTAACATAGTTTGTCTCCTAGATGTCCTCATGCAAGATTCAAGGTTGTATCTTATCTTTGAGTTTCTCTCCATGGATCTAAAGAAGTATTTGGACTCCATACCCAGCGGCCAGTATATAGATACGATGCTCGTTAAGAGTTACCTATACCAGATCCTACAAGGCATTGTATTTTGCCACTCCAGAAGAGTGCTACACAGAGACCTGAAACCTCAGAACCTGCTCATCGACAGCAAGGGAGTGATAAAGTTGGCAGATTTTGGGCTTGCCAGAGCTTTCGGCATTCCAGTTCGGGTTTACACACATGAGGTAGTGACATTATGGTACAGAGCCCCAGAAGTGCTGTTGGGGTCAGTCCGATATTCCACGCCGGTTGATGTTTGGAGCATAGGAACCATTTTTGCTGAGATTGCCACAAAGAAACCCCTCTTCCACGGTGACTCTGAAATTGACCAGCTCTTCAGGATATTCAGAGCTTTGGGAACACCCAACAATGAGGTGTGGCCAGAAGTAGAATCTTTACAAGATTACAAGAACTCATTCCCCAAATGGAAAGGGGGGAGCTTGTCGGCGAACGTGAAAAATATCGATAAGGATGGGCTGGACCTACTGGCTAAAATGCTAATCTATGATCCAGCCAAGAGAATTTCCGCACGTAAAGCTTTGCTGCACCCCTACTTCGATGATTTGGATAAGTCCAGCCTTCCTGACAATCAGATTAGAAACTAACACATCGAGCGTAGTTTCTTTTGGGTTTCTGTATGGGAATCTTGATGTAAATCACTTTTTATTGTCTGTATGTGATATATATATGTGTGTGTGTTTGTCTCGTCTTCTGCTGCTGATATTGCTGCACCCTAAGTACTTATATATGCACCACACTCTAATGTAAATATGGACTTGCCAAACTTGTGTATAGATGCATCTCCACACTGACATTTCATTTCCAATAAAGCTTTATTGTATATTGCTG		Refseq >NM_001086624\|Xenopus laevis cyclin-dependent kinase 1 (cdk1-b), mRNA GGAGCAAGAGGAAGCGGCGCTGCAAGAGGGGTAGTCCAAACTTGGGAAACCGTCATGGACGAGTACACTAAAATAGAGAAGATTGGAGAGGGCACATATGGGGTCGTGTACAAGGGTCGTCACAAAGCAACCGGCCAGGTCGTCGCAATGAAGAAAATTAGATTGGAAAATGAAGAGGAAGGTGTCCCAAGTACAGCAATCCGAGAAATATCACTACTTAAAGAGCTTCAGCACCCCAACATAGTCTGCCTCCTAGATGTCCTCATGCAAGACTCAAGGTTGTATCTTATCTTTGAGTTTCTCTCCATGGATCTAAAGAAGTATTTAGACTCGATACCCAGCGGCCAGTATATCGATACAATGCTCGTTAAGAGTTACCTGTACCAGATCCTACAAGGGATTGTATTCTGTCACTCCAGACGAGTTCTACACAGAGACCTGAAACCTCAAAACCTGCTCATAGACAATAAAGGAGTGATAAAGTTGGCAGATTTTGGCCTTGCCAGAGCTTTTGGAATTCCGGTTCGGGTTTACACACACGAGGTCGTGACGTTATGGTACAGAGCCTCGGAAGTGCTGTTGGGGTCAGTCCGATATTCAACGCCAGTTGACGTCTGGAGCGTAGGAACTATTTTCGCCGAGATCGCCACAAAGAAACCCCTCTTCCACGGTGACTCTGAAATTGACCAGCTCTTCAGGATATTCAGATCTTTAGGGACACCCAACAATGAAGTGTGGCCAGAAGTAGAGTCTTTACAAGATTACAAGAACACATTCCCCAAATGGAAAGGGGGAAGCCTGTCGTCGAATGTGAAAAATATTGATGAGGATGGGCTGGACCTGCTGTCTAAAATGCTAGTCTATGATCCCGCCAAGAGGATTTCCGCACGAAAAGCTATGTTGCACCCCTACTTCGATGACTTGGATAAGTCCAGCCTTCCCGCCAATCAGATTAGAAATTAAAACGGCAAATGTTTGTTTCTTTGGGGTTTTTGGATGGGGGATCTGATGTAAATCACTCATTATTTTTTATTGTCTGTATGTGATATATATATGTATGTGTGTGTGTCTCGTCTTCTGCTGCTGATGTAGTGGCACCTCCAAGTACTTGTGTTAAAGCACCACACTCTAATGTAAATATGGACCTGCCAAACATGTGTATAAATGCAATTCCACACGGACATTTCATTTGCAATAAAGCTTTATTATATGTAGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_988908\|cell division cycle 2 [Xenopus (Silurana) tropicalis] MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKGGNLSANVKNIDKDGLDLLSKMLIYDPAKRISARKALLHPYFDDLDKSSLPANQIRN	Refseq >NP_001080554\|cyclin-dependent kinase 1-A [Xenopus laevis] MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDSKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRAPEVLLGSVRYSTPVDVWSIGTIFAEIATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNSFPKWKGGSLSANVKNIDKDGLDLLAKMLIYDPAKRISARKALLHPYFDDLDKSSLPDNQIRN UniProtKB		Refseq >NP_001080093\|cyclin-dependent kinase 1-B [Xenopus laevis] MDEYTKIEKIGEGTYGVVYKGRHKATGQVVAMKKIRLENEEEGVPSTAIREISLLKELQHPNIVCLLDVLMQDSRLYLIFEFLSMDLKKYLDSIPSGQYIDTMLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGIPVRVYTHEVVTLWYRASEVLLGSVRYSTPVDVWSVGTIFAEIATKKPLFHGDSEIDQLFRIFRSLGTPNNEVWPEVESLQDYKNTFPKWKGGSLSSNVKNIDEDGLDLLSKMLVYDPAKRISARKAMLHPYFDDLDKSSLPANQIRN UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.65705	Xl.8917 [+] Xl.22030		Xl.3815
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		3 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CDK1
mouse		MGI	Cdk1	All(7) Targeted, other(1) Gene Trapped(2) Targeted, knock Out(2)
zebrafish		ZFIN	cdk1	3 Lines(s)

Publications
First:		Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. [Cell 1988]
Most recent:		The role of APC/C inhibitor Emi2/XErp1 in oscillatory dynamics of early embryonic cell cycles. [Biophys Chem 2013]
		View All Papers 7 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		ATP binding cAMP-dependent protein kinase activity cAMP-dependent protein kinase regulator activity More[+] protein kinase CK2 activity protein kinase CK2 regulator activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity
Biological:		protein amino acid phosphorylation
Cellular Component:		cAMP-dependent protein kinase complex protein kinase CK2 complex
EC:		now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
KOG:		[R] Protein kinase PCTAIRE and related kinases

Reagents		tropicalis	laevis a		laevis b
Clones			EXRC - 2 clone(s)
		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.27631.1.S1_at	Xl.8917.1.S1_at		Xl.3815.1.S1_a_at
Affymetrix 2.0			Xl2.8917.1.S1_at		Xl2.3815.2.S1_a_at

Symbol legend[+]