Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (811) GO Terms (20) Nucleotides (372) Proteins (41) Interactants (1141) Wiki
XB-GENEPAGE- 482749

Gene Symbol: cdk1

Gene Name: cyclin-dependent kinase 1

Synonyms: p34cdc2 , cell division control protein 2 homolog , cdc-2 , xcdc2 , cdc2 , cdc28a , PSTAIR , cdc2x1.1 , maturation-promoting factor , MPF , cdk1-b , cdk1-a
Add Xenopus synonyms , Nomenclature history

Gene Function: serine/threonine kinase

Protein Function :
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C-ter...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
1/2
 

Xenbase Gene ID XB-GENE-482750 XB-GENE-6254942 XB-GENE-482754
Gene Symbol cdk1 cdk1.L cdk1.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.65705 Xl.3815 Xl.8917 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cdk1 cdk1.L cdk1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CDK1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cdk1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR cdk1 ZFIN Ensembl
chicken
GEISHA CDK1 Ensembl
fruit fly
FLYBASE Cdk1 Ensembl
worm
WORMBASE
Publications
First: Effects of cycloheximide on the "autocatalytic" nature of the maturation promoting factor (MPF) in oocytes of Xenopus laevis. [Cell 1975]
Most recent: Analysis of Mitotic Checkpoint Function in Xenopus Egg Extracts. [Cold Spring Harb Protoc 2018]
View All Papers 11 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 9 terms 9 terms
PANTHER cdk1
KEGG Pathways K02087 K02087 K02087
KOG [R] Protein kinase PCTAIRE and related kinases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones     EXRC - 2 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Cdk1 Ab2 Cdk1 Ab2 Cdk1 Ab2
ORF cdk1 ORF1 , cdk1 ORF1 cdk1.L ORF1 cdk1.S ORF1
Affymetrix 1.0 Str.27631.1.S1_at Xl.3815.1.S1_a_at Xl.8917.1.S1_at
Affymetrix 2.0 Xl2.3815.2.S1_a_at Xl2.8917.1.S1_at

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.2
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556