Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (832) GO Terms (39) Nucleotides (397) Proteins (60) Interactants (1297) Wiki
XB-GENEPAGE-482749
Gene Symbol:
cdk1

Gene Name:
cyclin-dependent kinase 1

Synonyms:
p34cdc2 , cell division control protein 2 homolog , cdc-2 , xcdc2 , cdc2 , cdc28a , PSTAIR , cdc2x1.1 , maturation-promoting factor , MPF , cdk1-b , cdk1-a ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C-ter...[+]


InterPro :
GNAT dom , Acyl CoA acyltransferase , Furin repeat , Rcpt L-dom sf [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-482750 XB-GENE-6254942 XB-GENE-482754
Gene Symbol cdk1 cdk1.L cdk1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394503
379785
380246
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdk1 cdk1.L cdk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards CDK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdk1 Ensembl
zebrafish
ZFIN, AGR cdk1 ZFIN Ensembl
chicken
GEISHA CDK1 Ensembl
fruit fly
FLYBASE Cdk1 Ensembl
Publications
First Effects of cycloheximide on the "autocatalytic" nature of the maturation promoting factor (MPF) in oocytes of Xenopus laevis., Cell 1975      
Most Recent Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation., Curr Biol 2021                                
All View All Papers 12 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 33 terms 12 terms 12 terms
PANTHER cdk1
KEGG Pathways K02087 K02087 K02087
KOG [R] Protein kinase PCTAIRE and related kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdk1
Antibodies Cdk1 Ab2 Cdk1 Ab2 Cdk1 Ab2
ORFs cdk1 ORF1 cdk1.L ORF1 cdk1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info