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Summary Expression Gene Literature (827) GO Terms (27) Nucleotides (393) Proteins (58) Interactants (1279) Wiki
XB-GENEPAGE-482749
Gene Symbol:
cdk1

Gene Name:
cyclin-dependent kinase 1

Synonyms:
p34cdc2 , cell division control protein 2 homolog , cdc-2 , xcdc2 , cdc2 , cdc28a , PSTAIR , cdc2x1.1 , maturation-promoting factor , MPF , cdk1-b , cdk1-a ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C-ter...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-482750 XB-GENE-6254942 XB-GENE-482754
Gene Symbol cdk1 cdk1.L cdk1.S
Chromosome Chr07 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394503
379785
380246
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cdk1 cdk1.L cdk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CDK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cdk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cdk1 Ensembl
zebrafish
ZFIN, AGR cdk1 ZFIN Ensembl
chicken
GEISHA CDK1 Ensembl
fruit fly
FLYBASE Cdk1 Ensembl
worm
Publications
First Effects of cycloheximide on the "autocatalytic" nature of the maturation promoting factor (MPF) in oocytes of Xenopus laevis., Cell 1975      
Most Recent The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos., Development 2020                              
All View All Papers 12 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 23 terms 10 terms 10 terms
PANTHER cdk1
KEGG Pathways K02087 K02087 K02087
KOG [R] Protein kinase PCTAIRE and related kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cdk1
Antibodies Cdk1 Ab2 Cdk1 Ab2 Cdk1 Ab2
ORFs cdk1 ORF1 cdk1.L ORF1 cdk1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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