smad2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (147)

Nucleotides (163)

Interactants (301)

XB-GENEPAGE-482929

Gene Symbol: smad2 Gene Name: SMAD family member 2 Synonyms: XSmad2, smad-2 Add Xenopus synonyms Gene Function: signal transduction, TGF-beta pathway Interactants: tgfb1(82) , smad4.2(59) , smad4.1(57) , nodal(47) , smad1(47) , smad3(42) , t(28) View All

XB-GENE-482930

XB-GENE-864923

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001011168\|Xenopus (Silurana) tropicalis SMAD family member 2 (smad2), mRNA AAGGATAACAATAATATATAGAGAAAGGGGAACAGGAACCCGGTGCCCGCTGGGGCTTTGGGGGCCGAGGCGCTAAGGGCCCGTCTGTATGAGCGGGGGCTTCCTCTGCCGCCATCTTGGTTCGGGGTCGTTGTTGCGTATTTCCCCCTCCTCCCTCCTGTCCAGTTAGGCCTGACCGGGCCGGGGAGCCGCCACATCTTCAGACAAGTGGATCAGAAACTGCCCTACAGCTGCGGTAGCAGTGGCAAAACATGTCCTCCATTTTGCCATTTACCCCGCCAGTTGTGAAGCGCCTGTTAGGATGGAAGAAGTCACCAAGTGGCACCACTGGCGCGGGTGGCGGTGAGCAGAACGGACAGGAAGAAAAGTGGTGCGAAAAAGCGGTAAAAAGCTTGGTGAAAAAACTAAAGAAAACGGGACAATTAGATGAGCTTGAGAAAGCCATAACGACTCAGAACTGCAACACGAAATGCGTAACGATACCAAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACCATAGATCAGTGGGATACCACAGGCCTTTACAGCTTCTCTGAACAAACCAGGTCTCTTGATGGTCGGCTCCAGGTGTCCCACCGCAAAGGATTGCCCCACGTTATCTACTGCCGACTGTGGCGCTGGCCAGACCTGCACAGTCATCACGAACTGAAAGCGATCGAAAATTGTGAATATGCTTTTAACCTTAAAAAAGATGAAGTGTGTGTCAATCCTTATCATTATCAAAGGGTCGAGACACCAGTCTTACCACCTGTATTAGTTCCACGGCACACAGAGATCTTGACAGAGCTGCCACCTCTTGATGACTACACGCATTCCATTCCAGAAAACACTAATTTTCCTGCAGGAATTGAACCTCAGAGCAATTATATTCCAGAAACACCACCTCCTGGATATATTAGTGAAGATGGAGAAACTAGCGATCAGCAACTTAACCAAAGCATGGACACAGGGTCACCAGCTGAGCTGTCTCCGAGTACACTTTCTCCCGTCAACCACAATCTTGATTTGCAACCAGTCACCTATTCGGAACCTGCTTTTTGGTGCTCCATAGCATACTATGAACTGAATCAGCGAGTGGGAGAAACTTTCCATGCGTCGCAACCTTCGCTTACCGTGGACGGCTTCACGGACCCCTCAAACTCTGAAAGGTTCTGTTTAGGTTTACTCTCAAATGTGAACCGAAATGCCACGGTGGAAATGACCAGGCGTCATATAGGAAGAGGAGTCCGGCTATATTACATCGGGGGCGAGGTGTTTGCAGAGTGCCTAAGTGATAGTGCTATATTTGTCCAGAGTCCAAACTGTAACCAGCGGTATGGTTGGCATCCAGCAACTGTATGTAAGATACCTCCAGGATGCAATCTGAAGATTTTTAATAACCAAGAGTTTGCTGCTCTCCTCGCTCAGTCTGTGAATCAAGGCTTCGAAGCAGTTTATCAGTTAACTCGAATGTGCACCATAAGAATGAGCTTTGTAAAAGGCTGGGGTGCTGAATACAGGCGTCAGACCGTTACAAGCACTCCATGTTGGATCGAGCTTCACCTGAACGGACCTTTGCAGTGGTTGGACAAAGTGTTGACACAGATGGGATCCCCTTCAGTGCGCTGCTCAAGCATGTCCTAATGGGCGCTTCTTTTATGTATTACCTGTGGGTGGCAACCGAAGTCCCAGCAACAGACTCAATACAGCTTGTCTGTCATAGTATTTGTGTGTGGTCCCCATGAACTGTTTACAATCCAAAAGAAAAAAAAACAAAAAACCAAAAGCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001091495\|Xenopus laevis SMAD family member 2 (smad2), mRNA CTCCAGATAAGAAGCAGATCTAAATCCTATAGCAGCAGTGGCAAAACATGTCCTCGATTTTGCCATTCACCCCACCAGTTGTGAAGCGCCTGTTAGGATGGAAGAAGTCAGCAAGCGGCACCACTGGAGCAGGTGGAGGTGAGCAGAACGGTCAGGAAGAGAAGTGGTGCGAGAAAGCCGTAAAGAGTTTGGTGAAAAAACTGAAGAAAACGGGACAATTAGACGAGCTTGAGAAAGCAATAACGACACAGAACTGCAACACAAAATGCGTGACAATACCAAGCACTTGCTCTGAAATTTGGGGACTGAGTACACCAAATACCATAGATCAGTGGGATACCACAGGCCTTTACAGCTTCTCTGAACAAACCAGGTCTCTTGATGGTCGACTCCAGGTGTCTCACCGTAAAGGATTGCCCCACGTTATCTACAGCCGGCTGTGGCGCTGGCCAGACCTGCACAGTCATCACGAACTGAAAGCAGTCGAAAATTGTGAATATGCTTTTAACCTTAAAAAAGATGAAGTATGTGTCAATCCTTACCATTATCAGAGGGTAGAGACACCAGTTTTACCGCCGGTATTAGTTCCACGGCACACAGAAATCTTGACAGAGCTGCCACCTCTTGATGACTACACGCATTCCATTCCAGAAAACACTAATTTTCCTGCAGGAATTGAACCTCAGAGCAATTATATTCCAGAAACACCACCTCCTGGATATATTAGTGAAGATGGAGAAACTAGCGATCAGCAACTTAACCAAAGCATGGACACAGGGTCGCCAGCTGAGCTGTCTCCGAGTACGCTTTCTCCAGTCAACCACAATCTCGATTTGCAACCTGTCACCTATTCGGAACCTGCTTTTTGGTGCTCTATAGCATACTATGAACTGAATCAGCGAGTGGGAGAAACTTTCCATGCATCGCAACCGTCTCTTACCGTGGACGGCTTTACAGACCCCTCAAACTCTGAAAGGTTCTGTTTAGGTTTACTCTCAAATGTGAACCGGAATGCCACGGTGGAAATGACCAGGCGTCATATAGGAAGAGGAGTCCGGCTATATTACATCGGTGGAGAGGTGTTTGCAGAGTGCCTAAGTGATAGTGCTATTTTTGTCCAGAGTCCAAACTGTAACCAGCGGTATGGTTGGCATCCAGCAACTGTATGTAAGATACCTCCAGGATGCAATCTGAAGATTTTTAATAACCAAGAGTTTGCTGCTCTCCTCGCTCAGTCGGTGAATCAAGGCTTTGAAGCAGTTTATCAGTTAACGCGAATGTGCACCATAAGGATGAGCTTTGTAAAAGGCTGGGGTGCTGAATACAGGCGACAGACCGTTACAAGCACTCCATGCTGGATTGAGCTTCACCTGAATGGACCTTTGCAGTGGTTGGACAAAGTGTTGACACAGATGGGATCCCCTTCAGTCCGCTGCTCAAGCATGTCCTAATGGTCTCCTCTTTTATGTATTACCTGTGGGCGGCAACTGTAGTCCCAGCAACAGACTCGATTCAGTTTGTCTGTCATAGTATTTGTGTGTGGTCCCCATGAACTGTTTACAATCCAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001011168\|SMAD family member 2 [Xenopus (Silurana) tropicalis] MSSILPFTPPVVKRLLGWKKSPSGTTGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPSTLSPVNHNLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS	Refseq >NP_001084964\|SMAD family member 2 [Xenopus laevis] MSSILPFTPPVVKRLLGWKKSASGTTGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSHRKGLPHVIYSRLWRWPDLHSHHELKAVENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPSTLSPVNHNLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.11098	Xl.60962
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		9 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tegg118f13

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SMAD2
mouse		MGI	Smad2	All(23) Targeted, knock Out(11) Targeted, other(10) Chemically Induced(1)
zebrafish		ZFIN	smad2	1 Lines(s)

Publications
First:		Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. [Nature 1996]
Most recent:		The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1. [Genes Dev 2013]
		View All Papers 25 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		intracellular
EC:
KOG:		[TK] TGFbeta receptor signaling protein SMAD and related proteins

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.11098.2.S1_a_at [+] Str.25230.1.A1_x_at Str.11098.2.S2_at
Affymetrix 2.0			Xl2.85.1.S1_s_at

Symbol legend[+]