Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (624) GO Terms (34) Nucleotides (199) Proteins (40) Interactants (2082) Wiki
XB-GENEPAGE-483057

Gene Symbol: bmp4

Gene Name: bone morphogenetic protein 4

Synonyms: XBMP-4 , bmp-4 , xbmp4 , zyme , bmp2b , ofc11 , bmp2b1 , DVR-4 , bmp4-a , bmp4-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: TGF-beta related peptide growth factor

Protein Function :
Posterior-ventralizing factor in Xenopus mesoderm induction. Induces posteroventral mesoderm and counteracts dorsalizing signals such as activin.

Interactants: Loading ...
Disease Ontology: microphthalmia

OMIM Diseases: MICROPHTHALMIA, SYNDROMIC 6; MCOPS6 [+]

1/9
 
Xenbase Gene ID XB-GENE-483058 XB-GENE-483062 XB-GENE-6254046
Gene Symbol bmp4 bmp4.L bmp4.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine bmp4 bmp4.L bmp4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu045c17      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards BMP4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Bmp4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR bmp4 ZFIN Ensembl
chicken
GEISHA BMP4 Ensembl
fruit fly
worm
WORMBASE
Publications
First Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse., Development 1991  
Most Recent Hematopoiesis: from start to immune reconstitution potential., Stem Cell Res Ther null  
All View All Papers 96 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 29 terms 3 terms 9 terms
PANTHER bmp4
KEGG Pathways K04662 K04662 K04662
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 2 clone(s)  
Dharmacon Dharmacon Dharmacon
Morpholino bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4 bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4 bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4
ORF bmp4.L ORF1
Affymetrix 1.0 Str.26831.1.S1_s_at [+] Xl.10632.1.A1_at [+]
Affymetrix 2.0 Xl2.4619.1.S1_s_at [+] Xl2.1141.1.S1_x_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.2


Major funding for Xenbase is provided by grant P41 HD064556