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Summary Expression Gene Literature (607) GO Terms (33) Nucleotides (190) Proteins (37) Interactants (1375) Wiki
XB-GENEPAGE- 483057

Gene Symbol: bmp4

Gene Name: bone morphogenetic protein 4

Synonyms: XBMP-4 , bmp-4 , xbmp4 , bone morphogenetic protein-4 , zyme , bmp2b , ofc11 , bmp2b1 , DVR-4 , bmp4-a , bmp4-b
Add Xenopus synonyms , Nomenclature history

Gene Function: TGF-beta related peptide growth factor

Protein Function:
Posterior-ventralizing factor in Xenopus mesoderm induction. Induces posteroventral mesoderm and counteracts dorsalizing signals such as activin.


Interactants: YYY

OMIM Disease Associations: MICROPHTHALMIA, SYNDROMIC 6; MCOPS6
1/9
 
Xenbase Gene ID XB-GENE-483058 XB-GENE-483062 XB-GENE-6254046
Gene Symbol bmp4 bmp4.L bmp4.S
Chromosome scaffold_8 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.490 Xl.4619 Xl.1141 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 180 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine bmp4 bmp4.L bmp4.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu045c17      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards BMP4 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Bmp4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN bmp4 ZFIN Ensembl
chicken
GEISHA BMP4 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse. [Development 1991]
Most recent: Lineage commitment of embryonic cells involves MEK1-dependent clearance of pluripotency regulator Ventx2. [Elife 2017]
View All Papers 96 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 28 terms 3 terms 9 terms
EC
PANTHER bmp4
KEGG Pathways K04662 K04662 K04662
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 2 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4 bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4 bmp4 MO1 , bmp4 MO2 , bmp4 MO3 , bmp4 MO4
ORF bmp4 ORF1
Affymetrix 1.0 Str.26831.1.S1_s_at [+] Xl.10632.1.A1_at [+]
Affymetrix 2.0 Xl2.4619.1.S1_s_at [+] Xl2.1141.1.S1_x_at [+]

Symbol legend[+]

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