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Summary Expression Gene Literature (25) GO Terms (4) Nucleotides (67) Proteins (25) Interactants (276) Wiki
XB-GENEPAGE- 483145

Gene Symbol: six6

Gene Name: SIX homeobox 6

Synonyms: XOptx2 , Six6.1 , Six6.2 , xSix6 , optx2
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:


Interactants: YYY

OMIM Disease Associations: MICROPHTHALMIA, ISOLATED, WITH CATARACT 2; MCOPCT2
 
Xenbase Gene ID XB-GENE-483146 XB-GENE-864947 XB-GENE-1021810
Gene Symbol six6 six6.L six6.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.21495 Xl.533 Xl.21925 Xl.21533 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 22 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine six6 six6.L six6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SIX6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Six6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN six6a six6b ZFIN Ensembl
chicken
GEISHA SIX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Giant eyes in Xenopus laevis by overexpression of XOptx2. [Cell 1999]
Most recent: Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of the Xenopus laevis homoeologs six6.L and six6.S. [Dev Biol 2017]
View All Papers 8 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 4 terms
EC
PANTHER six6
KEGG Pathways K19473 K19473 K19473
KOG [K] Transcription factor SIX and related HOX domain proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
ORF six3 ORF1
Affymetrix 1.0 Str.21495.1.S1_at Xl.533.1.S1_at Xl.21925.1.S1_at
Affymetrix 2.0 Xl2.533.1.S1_at Xl2.21925.1.S1_at [+]

Symbol legend[+]

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