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Summary Expression Gene Literature (448) GO Terms (4) Nucleotides (36) Proteins (17) Interactants (1280) Wiki
XB-GENEPAGE-483208

Gene Symbol: nodal

Gene Name: nodal growth differentiation factor

Synonyms: Xnr-4 , Xnr4 , nr4 , nodal4 , Nodal homolog 4 ( Add Xenopus synonyms , Nomenclature history )

Gene Function: transforming growth factor beta and bone morphogenetic protein related protein

Protein Function :
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos. Plays a role in mesoderm formation and may be required for neural development.

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: NODAL, MOUSE, HOMOLOG OF; NODAL [+]
 
Xenbase Gene ID XB-GENE-483209 XB-GENE-864954 XB-GENE-17339551
Gene Symbol nodal nodal.L nodal.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq NCBI Nucleotide
Protein NCBI Protein TrEMBL Refseq Swiss-Prot Swiss-Prot NCBI Protein Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine nodal nodal.L nodal.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas097d22      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards NODAL OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Nodal MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ndr2 ZFIN Ensembl
chicken
GEISHA NODAL Ensembl
fruit fly
worm
WORMBASE
Publications
First Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments., Acta Physiol Scand 1973  
Most recent Spiral waves and vertebrate embryonic handedness., J Biosci 2018  
All View All Papers 90 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 4 terms 2 terms
PANTHER nodal
KEGG Pathways K04666 K04666 K04666
KOG [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Affymetrix 1.0 StrEns.4645.1.S1_at Xl.378.1.S1_at
Affymetrix 2.0 Xl2.378.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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