Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (47) GO Terms (14) Nucleotides (482) Proteins (49) Interactants (1003) Wiki
XB-GENEPAGE-483417
Gene Symbol:
sox11

Gene Name:
SRY-box 11

Synonyms:
xSOX-11 , XLS13 , XLS13b , xsox11 , xls13a , sox11-a , sox11-b ( Add synonyms , Nomenclature history )

Gene Function:
HMG-box transcription factor

Protein Function :
Transcription factor that binds to the DNA sequence 5'-AACAAT-3' (PubMed:9332350). Acts as a transcriptional activator. Plays a role together with nlk in neural induction during early embryogenesis (Pu...[+]


InterPro :
HMG box dom sf , HMG box dom , SOX-11 , SOX-11/4

Interactants:
Loading ...

Diseases: 


Disease Ontology:
autosomal dominant non-syndromic intellectual disability 27

OMIM:
MENTAL RETARDATION, AUTOSOMAL DOMINANT 27; MRD27

External Links:
1/5
 
Xenbase Gene ID XB-GENE-483418 XB-GENE-6252061 XB-GENE-483422
Gene Symbol sox11 sox11.L sox11.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 493415
100216330
399440
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot Swiss-Prot RefSeq Swiss-Prot Swiss-Prot Swiss-Prot
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine sox11 sox11.L sox11.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SOX11 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sox11 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sox11 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR sox11a sox11b ZFIN Ensembl
chicken
GEISHA SOX11 Ensembl
fruit fly
worm
Publications
First XLS13A and XLS13B: SRY-related genes of Xenopus laevis., Gene 1997  
Most Recent Natural size variation among embryos leads to the corresponding scaling in gene expression., Dev Biol 2020                      
All View All Papers 9 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 7 terms 5 terms
PANTHER sox11
KEGG Pathways K09268 K09268 K09268
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sox11
Morpholinos sox11 MO1 , sox11 MO2 sox11 MO1 , sox11 MO2 sox11 MO1 , sox11 MO2
ORFs sox11 ORF1 sox11.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556