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Summary Expression Gene Literature (88) GO Terms (22) Nucleotides (113) Proteins (56) Interactants (1084) Wiki
Gene Symbol: pax8

Gene Name: paired box 8

Synonyms: XPax8 , XPax-8 , pax-8 ( Add synonyms , Nomenclature history )

Gene Function: paired box transcription factor

Protein Function :
Probable transcription factor. Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae.

Interactants: Loading ...
Diseases:  Disease Ontology: congenital nongoitrous hypothryoidism 2


External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-483693 XB-GENE-865008 XB-GENE-17334490
Gene Symbol pax8 pax8.L pax8.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 780226
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot TrEMBL RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine pax8 pax8.L pax8.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards PAX8 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Pax8 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR pax8 ZFIN Ensembl
fruit fly
First Molecular regulation of pronephric development., Curr Top Dev Biol 1999      
Most Recent A Critical E-box in Barhl1 3'' Enhancer Is Essential for Auditory Hair Cell Differentiation., Cells 2019                
All View All Papers 31 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 19 terms 4 terms
KEGG Pathways K09293 K09293 K09293
KOG [K] Transcription factor PAX2/5/8, contains PAX domain
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pax8
Antibodies Pax8 Ab1 Pax8 Ab1
Morpholinos pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3 pax8 MO1 , pax8 MO2 , pax8 MO3
ORFs pax8 ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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