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Summary Expression Gene Literature (106) GO Terms (17) Nucleotides (360) Proteins (32) Interactants (743) Wiki
XB-GENEPAGE- 483730

Gene Symbol: fzd7

Gene Name: frizzled class receptor 7

Synonyms: Fz-7 , Xfz7 , frizzled-7 , frizzled7 , frizzled 7 , frz7 , frz-7 , fz7
Add Xenopus synonyms , Nomenclature history


Gene Function: transmembrane receptor in the wnt signaling pathway

Protein Function:
Receptor for Wnt proteins. Acts in both canonical and non-canonical Wnt pathways. Although different papers report differing Wnt preferences, wnt5a, wnt8b and wnt11 have been proposed as synergists. In...[+]


Interactants: YYY

OMIM Disease Associations:
1/8
 
Xenbase Gene ID XB-GENE-483731 XB-GENE-483735 XB-GENE-17333315
Gene Symbol fzd7 fzd7.L fzd7.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.48717 [+] Xl.633 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 70 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fzd7 fzd7.L fzd7.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tneu065e03      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FZD7 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Fzd7 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN fzd7a fzd7b ZFIN Ensembl
chicken
GEISHA FZD7 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Two novel Xenopus frizzled genes expressed in developing heart and brain. [Mech Dev 1999]
Most recent: PTK7 localization and protein stability is affected by canonical Wnt ligands. [J Cell Sci 2017]
View All Papers 32 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 16 terms 0 term
EC
PANTHER fzd7
KEGG Pathways K02432 K02432
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones   EXRC - 5 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino fzd7 MO1 , fzd7 MO2 , fzd7 MO3 , fzd7 MO4 , fzd7 MO5 , fzd7 MO6 , fzd7 MO7 fzd7 MO1 , fzd7 MO2 , fzd7 MO3 , fzd7 MO4 , fzd7 MO5 , fzd7 MO6 , fzd7 MO7 fzd7 MO1 , fzd7 MO2 , fzd7 MO3 , fzd7 MO4 , fzd7 MO5 , fzd7 MO6 , fzd7 MO7
Affymetrix 1.0 Str.6502.1.S1_s_at Xl.633.2.S2_at [+]
Affymetrix 2.0 Xl2.633.2.S2_at [+]

Symbol legend[+]

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