Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (129) GO Terms (7) Nucleotides (84) Proteins (32) Interactants (754) Wiki
XB-GENEPAGE-483869
Gene Symbol: dvl1

Gene Name: dishevelled segment polarity protein 1

Synonyms: dsh1 , dishevelled1 , Xdsh , dsh ( Add synonyms , Nomenclature history )

Gene Function: cytoplasmic phosphoprotein, wnt signal transduction

Protein Function :

Interactants: Loading ...
Diseases:  Disease Ontology: autosomal dominant Robinow syndrome 1

OMIM: ROBINOW SYNDROME, AUTOSOMAL DOMINANT 1; DRS1 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/3
 
Xenbase Gene ID XB-GENE-483870 XB-GENE-865024 XB-GENE-17330253
Gene Symbol dvl1 dvl1.L dvl1.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 100144639
100381153
mRNA RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine dvl1 dvl1.L dvl1.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DVL1 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dvl1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR dvl1a dvl1b ZFIN Ensembl
chicken
GEISHA DVL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled., Development 1995                
Most Recent The tumor suppressor PTPRK promotes ZNRF3 internalization and is required for Wnt inhibition in the Spemann organizer., Elife 2020                                                          
All View All Papers 26 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 3 terms 0 term
PANTHER dvl1
KEGG Pathways K02353
KOG [R] Dishevelled 3 and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dvl1
Antibodies dvl1 Ab1 dvl1 Ab1 dvl1 Ab1
Morpholinos dvl1 MO1 , dvl1 MO2 dvl1 MO1 , dvl1 MO2 dvl1 MO1 , dvl1 MO2
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.1
Major funding for Xenbase is provided by grant P41 HD064556