Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (7) GO Terms (7) Nucleotides (47) Proteins (25) Interactants (641) Wiki
XB-GENEPAGE-483933

Gene Symbol: sox6

Gene Name: SRY-box 6

Synonyms: ( Add Xenopus synonyms , Nomenclature history )

Gene Function: HMG-box transcription factor

Protein Function :
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

Interactants: Loading ...
Disease Ontology:

OMIM Diseases:

1/2
 
Xenbase Gene ID XB-GENE-483934 XB-GENE-17337583 XB-GENE-17337584
Gene Symbol sox6 sox6.L sox6.S
Chromosome scaffold_66 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL TrEMBL Swiss-Prot RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine sox6 sox6.L sox6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Sox6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
sox6 ZFIN Ensembl
chicken
GEISHA SOX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells., Mol Cell Biol 2007                  
Most Recent Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Dev Biol 2018                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 0 term 4 terms
PANTHER sox6
KEGG Pathways K09269
KOG [K] HMG-box transcription factor SOX5
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino sox6 MO1 sox6 MO1 sox6 MO1
Affymetrix 1.0 Str.35208.1.A1_at
Affymetrix 2.0

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.3


Major funding for Xenbase is provided by grant P41 HD064556