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XB-GENEPAGE-
483949
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Gene Symbol: tacc3
Gene Name: transforming acidic coiled-coil containing protein 3 Synonyms: maskin , xmaskin , eric1 Add Xenopus synonyms , Nomenclature history Gene Function: Projectin/twitchin and related proteins Protein Function  :
Maternal RNA in oocytes remains in a dormant state as masking outcompetes eif4g to bind eif4e, thereby preventing translation. During oocyte maturation this complex dissolves and eif4g binds eif4e to a...[+]
Interactants: Loading ... 
OMIM Disease Associations: BLADDER CANCER |
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| Xenbase Gene ID | XB-GENE-483950 | XB-GENE-17343957 | XB-GENE-865032 | ||||||||||
| Gene Symbol | tacc3 | tacc3.L | tacc3.S | ||||||||||
| Chromosome | Chr01 | chr1L | chr1S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
TrEMBL
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Refseq
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.5836 | Xl.25749 Xl.60072 | |||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 6 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | tacc3 | tacc3.L | tacc3.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
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| Publications | |||||||||||||
| First: | Maskin is a CPEB-associated factor that transiently interacts with elF-4E. [Mol Cell 1999] | ||||||||||||
| Most recent: |
The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. [Neural Dev 2017]
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| View All Papers 2 paper(s) referencing morpholinos | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 5 terms | 0 term | 8 terms | ||||||||||
| PANTHER | tacc3 | ||||||||||||
| KEGG Pathways | K14283 | K14283 | |||||||||||
| KOG |
[Z] Projectin/twitchin and related proteins
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
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| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | ||||||||||||
| Antibody | Tacc3 Ab1 , Tacc3 Ab2 | Tacc3 Ab1 , Tacc3 Ab2 | |||||||||||
| Morpholino | tacc3 MO1 , tacc3 MO2 | tacc3 MO1 , tacc3 MO2 | tacc3 MO1 , tacc3 MO2 | ||||||||||
| ORF | tacc3 ORF1 | ||||||||||||
| Affymetrix 1.0 | Str.5836.1.S1_a_at | Xl.580.1.S1_at | |||||||||||
| Affymetrix 2.0 | Xl2.580.1.S1_a_at | ||||||||||||
Symbol legend[+]
