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Summary Expression Gene Literature (54) GO Terms (11) Nucleotides (323) Proteins (50) Interactants (291) Wiki
XB-GENEPAGE-483949
Gene Symbol:
tacc3

Gene Name:
transforming acidic coiled-coil containing protein 3

Synonyms:
maskin , xmaskin , eric1 ( Add synonyms , Nomenclature history )

Gene Function:
Projectin/twitchin and related proteins

Protein Function :
Maternal RNA in oocytes remains in a dormant state as masking outcompetes eif4g to bind eif4e, thereby preventing translation. During oocyte maturation this complex dissolves and eif4g binds eif4e to a...[+]



Interactants:
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Diseases: 


Disease Ontology:
urinary bladder cancer

OMIM:
BLADDER CANCER

External Links:
 
Xenbase Gene ID XB-GENE-483950 XB-GENE-17343957 XB-GENE-865032
Gene Symbol tacc3 tacc3.L tacc3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 446220
779334
398145
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tacc3 tacc3.L tacc3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TACC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tacc3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tacc3 Ensembl
zebrafish
ZFIN, AGR tacc3 ZFIN Ensembl
chicken
GEISHA TACC3 Ensembl
fruit fly
worm
Publications
First Maskin is a CPEB-associated factor that transiently interacts with elF-4E., Mol Cell 1999  
Most Recent Investigating the impact of the phosphorylation status of tyrosine residues within the TACC domain of TACC3 on microtubule behavior during axon growth and guidance., Cytoskeleton (Hoboken) 2020  
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 1 terms 7 terms
PANTHER tacc3
KEGG Pathways K14283 K14283
KOG [Z] Projectin/twitchin and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tacc3
Antibodies Tacc3 Ab1 , Tacc3 Ab2 Tacc3 Ab1 , Tacc3 Ab2
Morpholinos tacc3 MO1 , tacc3 MO2 tacc3 MO1 , tacc3 MO2 tacc3 MO1 , tacc3 MO2
ORFs tacc3.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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