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XB-GENEPAGE-483982
Gene Symbol:
smarca4
Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms:
BRG1
,
snf2
,
snf2-beta
,
swi2
,
rtps2
,
baf190
,
snf2l4
,
snf2l4
,
snf2lb
,
snf2b
,
X-brg1
( Gene Function: chromatin remodeling complex component Protein Function
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The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain...[+]
Interactants:
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Diseases: Disease Ontology:
Coffin-Siris syndrome
OMIM:
COFFIN-SIRIS SYNDROME 4; CSS4
External Links:
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Xenbase Gene ID | XB-GENE-483983 | XB-GENE-17342693 | XB-GENE-865035 | |||||
Gene Symbol | smarca4 | smarca4.L | smarca4.S | Chromosome | Chr3 | Scaffold81 | Scaffold20 | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
496545
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108705241
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100335135
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | smarca4 | smarca4.L | smarca4.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Systematic identification of mitotic phosphoproteins., Curr Biol 1997 |
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Most Recent |
Cryo-EM structure of SWI/SNF complex bound to a nucleosome., Nature 2020 ![]() |
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All | View All Papers 4 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 16 terms | 7 terms | 7 terms | |||||
PANTHER | smarca4 | |||||||
KEGG Pathways | K11647 | K11647 | ||||||
KOG |
[BK] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | smarca4 | |||||||
Morpholinos (on-target & off-target) | smarca4 MO2 , smarca4 MO3 , smarca4 MO4 | smarca4 MO2 , smarca4 MO3 , smarca4 MO4 | smarca4 MO2 , smarca4 MO3 , smarca4 MO4 | |||||
Clones | Horizon | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



