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Summary Expression Gene Literature (38) GO Terms (16) Nucleotides (531) Proteins (50) Interactants (299) Wiki
XB-GENEPAGE-483982
Gene Symbol:
smarca4

Gene Name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Synonyms:
BRG1 , snf2 , snf2-beta , swi2 , rtps2 , baf190 , snf2l4 , snf2l4 , snf2lb , snf2b , X-brg1 ( Add synonyms , Nomenclature history )

Gene Function:
chromatin remodeling complex component

Protein Function :
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain...[+]


InterPro :
SnAC , Gln-Leu-Gln QLQ , P-loop NTPase , BRK domain [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Coffin-Siris syndrome [+]

OMIM:
COFFIN-SIRIS SYNDROME 4; CSS4 [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-483983 XB-GENE-17342693 XB-GENE-865035
Gene Symbol smarca4 smarca4.L smarca4.S
Chromosome Chr3 Scaffold81 Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496545
108705241
100335135
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smarca4 smarca4.L smarca4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMARCA4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smarca4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smarca4 Ensembl
zebrafish
ZFIN, AGR smarca4a ZFIN Ensembl
chicken
GEISHA SMARCA4 Ensembl
fruit fly
worm
Publications
First Systematic identification of mitotic phosphoproteins., Curr Biol 1997  
Most Recent Cryo-EM structure of SWI/SNF complex bound to a nucleosome., Nature 2020                          
All View All Papers 4 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 7 terms 7 terms
PANTHER smarca4
KEGG Pathways K11647 K11647
KOG [BK] Chromatin remodeling complex SWI/SNF, component SWI2 and related ATPases (DNA/RNA helicase superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smarca4
Morpholinos (on-target & off-target) smarca4 MO2 , smarca4 MO3 , smarca4 MO4 smarca4 MO2 , smarca4 MO3 , smarca4 MO4 smarca4 MO2 , smarca4 MO3 , smarca4 MO4
Clones Horizon Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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