Please note upcoming maintenance times for Xenbase - times are EST:

Wednesday 12-Dec-2018 before noon: BLAST, FTP (Xenbase will be partially functional)
Thursday 13-Dec-2018 before noon: Wiki, GBrowse, JBrowse (Xenbase will be partially functional)
Friday 14-Dec-2018 starting at 5 pm through weekend: Xenbase site and database (Xenbase will be completely down)

Click on this message to dismiss it.
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (282) GO Terms (5) Nucleotides (144) Proteins (41) Interactants (1534) Wiki

Gene Symbol: pax6

Gene Name: paired box 6

Synonyms: XLPAX6 , xpax6 , pax-6 , an2 , mgda , wagr , pax6-a , pax6-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: paired box transcription factor with homeodomain, involved in eye development

Protein Function :

Interactants: Loading ...
Disease Ontology: PETERS ANOMALY [+]

OMIM Diseases: ANIRIDIA 1; AN1 [+]
Xenbase Gene ID XB-GENE-484088 XB-GENE-865046 XB-GENE-6464331
Gene Symbol pax6 pax6.L pax6.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL TrEMBL Refseq TrEMBL TrEMBL Refseq TrEMBL TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images                   Ensembl In situ: Single cell: RNA-Seq:  
Data Mining tropicalis laevis.L laevis.S
XenMine pax6 pax6.L pax6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards PAX6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Pax6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ZFIN, AGR pax6a pax6b ZFIN Ensembl
fruit fly
First A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase., Proc Natl Acad Sci U S A 1987  
Most recent Identification of retinal homeobox (rax) gene-dependent genes by a microarray approach: The DNA endoglycosylase neil3 is a major downstream component of the rax genetic pathway., Dev Dyn 2018                              
All View All Papers 63 paper(s) referencing morpholinos 9 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 5 terms 5 terms
KEGG Pathways K08031 K08031 K08031
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
Clones EXRC - 1 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3
Transgene Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP)
Morpholino pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2
ORF pax6 ORF1 pax6.L ORF1
Affymetrix 1.0 Str.20625.1.S1_at [+] Xl.647.7.S1_at [+] Xl.647.4.S1_x_at [+]
Affymetrix 2.0 Xl2.647.7.S1_at [+] Xl2.647.3.S2_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.10.0

Major funding for Xenbase is provided by grant P41 HD064556