Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (308) GO Terms (20) Nucleotides (159) Proteins (61) Interactants (1714) Wiki
XB-GENEPAGE-484087
Gene Symbol: pax6

Gene Name: paired box 6

Synonyms: XLPAX6 , xpax6 , pax-6 , an2 , mgda , wagr , pax6-a , pax6-b ( Add synonyms , Nomenclature history )

Gene Function: paired box transcription factor with homeodomain, involved in eye development

Protein Function :
May be a transcription factor with important functions in eye and nasal development.

Interactants: Loading ...
Diseases:  Disease Ontology: Peters anomaly [+]

OMIM: ANTERIOR SEGMENT DYSGENESIS 1; ASGD1 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
1/6
 
Xenbase Gene ID XB-GENE-484088 XB-GENE-865046 XB-GENE-6464331
Gene Symbol pax6 pax6.L pax6.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448447
379100
100337586
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL TrEMBL RefSeq TrEMBL TrEMBL RefSeq TrEMBL TrEMBL TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pax6 pax6.L pax6.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PAX6 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pax6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR pax6a pax6b ZFIN Ensembl
chicken
GEISHA PAX6 Ensembl
fruit fly
worm
WORMBASE
Publications
First A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase., Proc Natl Acad Sci U S A 1987  
Most Recent miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Genesis 2020                          
All View All Papers 66 paper(s) referencing morpholinos 11 paper(s) referencing OMIMs 18 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 5 terms 5 terms
PANTHER pax6
KEGG Pathways K04555 [+] K08031 K08031
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pax6
Antibodies Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4
Transgenes Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP)
Morpholinos pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2
ORFs pax6 ORF1 pax6.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.0


Major funding for Xenbase is provided by grant P41 HD064556