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Summary Expression Gene Literature (311) GO Terms (20) Nucleotides (196) Proteins (74) Interactants (1735) Wiki
XB-GENEPAGE-484087
Gene Symbol:
pax6

Gene Name:
paired box 6

Synonyms:
XLPAX6 , xpax6 , pax-6 , an2 , mgda , wagr , pax6-a , pax6-b ( Add synonyms , Nomenclature history )

Gene Function:
paired box transcription factor with homeodomain, involved in eye development

Protein Function :
May be a transcription factor with important functions in eye and nasal development.



Interactants:
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Diseases: 


Disease Ontology:
anterior segment mesenchymal dysgenesis [+]

OMIM:
ANTERIOR SEGMENT DYSGENESIS 1; ASGD1 [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-484088 XB-GENE-865046 XB-GENE-6464331
Gene Symbol pax6 pax6.L pax6.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448447
379100
100337586
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pax6 pax6.L pax6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PAX6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pax6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pax6 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR pax6a pax6b ZFIN Ensembl
chicken
GEISHA PAX6 Ensembl
fruit fly
worm
Publications
First A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase., Proc Natl Acad Sci U S A 1987  
Most Recent Interplay of TRIM2 E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis., Cells 2020                                            
All View All Papers 66 paper(s) referencing morpholinos 12 paper(s) referencing OMIMs 21 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 5 terms 5 terms
PANTHER pax6
KEGG Pathways K04555 [+] K08031 K08031
KOG [K] Transcription factor PRD and related proteins, contain PAX and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks pax6
Antibodies Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4 Pax6 Ab1 , Pax6 Ab2 , Pax6 Ab3 , pax6 Ab4
Transgenes Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP) Tg(pax6:GFP;CMV:RFP) , Tg(pax6:GFP;CMV:RFP)
Morpholinos pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2 pax6 MO1 , pax6 MO2
ORFs pax6 ORF1 pax6.L ORF1
Clones EXRC Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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