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Summary Expression Gene Literature (58) GO Terms (28) Nucleotides (79) Proteins (39) Interactants (823) Wiki
XB-GENEPAGE-484097
Gene Symbol:
wnt4

Gene Name:
Wnt family member 4

Synonyms:
Xwnt4 , Xwnt-4 , wnt-4 ( Add synonyms , Nomenclature history )

Gene Function:
secreted growth factor/developmental regulator

Protein Function :
Ligand for members of the frizzled family of seven transmembrane receptors.


InterPro :
DSBA-like thioredoxin dom , Thioredoxin-like sf , HCCAis GSTk , Wnt4 [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
46 XX gonadal dysgenesis [+]

OMIM:
MAYER-ROKITANSKY-KUSTER-HAUSER SYNDROME; MRKH [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-484098 XB-GENE-865047 XB-GENE-17330384
Gene Symbol wnt4 wnt4.L wnt4.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100491282
397706
108697659
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wnt4 wnt4.L wnt4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards WNT4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wnt4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wnt4 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR wnt4 wnt4b ZFIN Ensembl
chicken
GEISHA WNT4 Ensembl
fruit fly
FLYBASE Wnt4 Ensembl
Publications
First Analysis of Xwnt-4 in embryos of Xenopus laevis: a Wnt family member expressed in the brain and floor plate., Development 1992                
Most Recent Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads., Differentiation 2018                            
All View All Papers 13 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 9 terms 4 terms
PANTHER wnt4
KEGG Pathways K00408 K00408
KOG [T] Wnt family of developmental regulators
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wnt4
Morpholinos wnt4 MO1
ORFs wnt4.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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