Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (9) GO Terms (4) Nucleotides (19) Proteins (9) Interactants (84) Wiki
XB-GENEPAGE- 484223

Gene Symbol: acvrl1

Gene Name: activin A receptor type 1

Synonyms: alk1 , alk-1 , hht2 , orw2 , skr3 , tsr-i , acvrlk1
Add Xenopus synonyms , Nomenclature history


Gene Function: activin receptor, serine/threonine protein kinase

Protein Function:


Interactants: Loading ...

OMIM Disease Associations: TELANGIECTASIA, HEREDITARY HEMORRHAGIC, TYPE 2; HHT2 PULMONA...
1/6
 
Xenbase Gene ID XB-GENE-484224 XB-GENE-17331298 XB-GENE-17331299
Gene Symbol acvrl1 acvrl1.L acvrl1.S
Chromosome scaffold_2 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide
Protein NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 8 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine acvrl1 acvrl1.L acvrl1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ACVRL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Acvrl1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN acvrl1 ZFIN Ensembl
chicken
GEISHA ACVRL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors. [Exp Cell Res 1996]
Most recent: Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage. [Proc Natl Acad Sci U S A 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 4 terms 0 term
EC now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
PANTHER acvrl1
KEGG Pathways K04675
KOG [T] Activin A type IB receptor, serine/threonine protein kinase
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Affymetrix 1.0 StrJgi.1938.1.S1_at
Affymetrix 2.0

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.7.1]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556