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Summary Expression Gene Literature (134) GO Terms (18) Nucleotides (300) Proteins (38) Interactants (1167) Wiki

Gene Symbol: sox17a

Gene Name: SRY-box 17 alpha

Synonyms: xSox17alpha1 , xSox17alpha2 , tSox17alpha , Xsox17-alpha , Sox17alpha , sox17-alpha , xsox17a , xsox17 , Xsox17alpha , sox17 alpha
Add Xenopus synonyms , Nomenclature history

Gene Function: HMG-box transcription factor

Protein Function :
Transcriptional activator. Binds to the DNA sequence 5'-AACAAT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in func...[+]

Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: SRY-BOX 17; SOX17 [+]
Xenbase Gene ID XB-GENE-484295 XB-GENE-865067 XB-GENE-6255435
Gene Symbol sox17a sox17a.L sox17a.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.114 [+] Xl.3831 Xl.11957
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 84 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine sox17a sox17a.L sox17a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards SOX17 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Sox17 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR sox17 ZFIN Ensembl
GEISHA SOX17 Ensembl
fruit fly
First: Xsox17alpha and -beta mediate endoderm formation in Xenopus. [Cell 1997]
Most recent: Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis. [Development 2018]
View All Papers 38 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 12 terms 14 terms 11 terms
PANTHER sox17a
KEGG Pathways K04495 K04495 K04495
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
Clones   EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Sox17a Ab1 Sox17a Ab1 Sox17a Ab1
Morpholino sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4
ORF sox17a.L ORF1 sox17a.S ORF1
Affymetrix 1.0 Str.114.1.S1_at Xl.3831.1.S1_at Xl.11957.1.S1_at
Affymetrix 2.0 Xl2.3831.1.S1_at Xl2.11957.1.S1_at

Symbol legend[+]
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