|
XB-GENEPAGE-
484294
|
Gene Symbol: sox17a
Gene Name: SRY-box 17 alpha Synonyms: xSox17alpha1 , xSox17alpha2 , tSox17alpha , Xsox17-alpha , Sox17alpha , sox17-alpha , xsox17a , xsox17 , Xsox17alpha , sox17 alpha Add Xenopus synonyms , Nomenclature history Gene Function: HMG-box transcription factor Protein Function  :
Transcriptional activator. Binds to the DNA sequence 5'-AACAAT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in func...[+]
Interactants: Loading ... 
Disease Ontology Associations: OMIM Disease Associations: SRY-BOX 17; SOX17 |
|
1/5 | Xenbase Gene ID | XB-GENE-484295 | XB-GENE-865067 | XB-GENE-6255435 | ||||||||||
| Gene Symbol | sox17a | sox17a.L | sox17a.S | ||||||||||
| Chromosome | Chr06 | chr6L | chr6S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
|
Genomic sequence
|
Genomic sequence
|
||||||||||
| CDS |
Gene model
|
||||||||||||
|
Entrez Gene
|
Entrez Gene
|
Entrez Gene
|
|||||||||||
| mRNA |
Refseq
|
Refseq
|
Refseq
|
||||||||||
| Protein
|
Refseq
Swiss-Prot
|
Refseq
Swiss-Prot
|
Refseq
Swiss-Prot
|
||||||||||
| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
|
||||||||||||
| Links |
|
||||||||||||
| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.114 [+] | Xl.3831 | Xl.11957 | ||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
|
|||||||||||
| Experimental regulation |
Regulation heatmap:
|
||||||||||||
| Images | 84 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | sox17a | sox17a.L | sox17a.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
|
||||||||||||
| human |
|
||||||||||||
| mouse |
|
||||||||||||
| zebrafish |
|
||||||||||||
| chicken |
|
||||||||||||
| fruit fly |
|
||||||||||||
| worm |
|
||||||||||||
| Publications | |||||||||||||
| First: |
Xsox17alpha and -beta mediate endoderm formation in Xenopus. [Cell 1997]
|
||||||||||||
| Most recent: |
Retinoic acid-induced expression of Hnf1b and Fzd4 is required for pancreas development in Xenopus laevis. [Development 2018]
|
||||||||||||
| View All Papers 38 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontologies | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 12 terms | 14 terms | 11 terms | ||||||||||
| PANTHER | sox17a | ||||||||||||
| KEGG Pathways | K04495 | K04495 | K04495 | ||||||||||
| KOG |
[K] HMG-box transcription factor
|
||||||||||||
| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
| Clones | EXRC - 1 clone(s) | ||||||||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | Source BioScience | |||||||||||
| Antibody | Sox17a Ab1 | Sox17a Ab1 | Sox17a Ab1 | ||||||||||
| Morpholino | sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 | sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 | sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 | ||||||||||
| ORF | sox17a.L ORF1 | sox17a.S ORF1 | |||||||||||
| Affymetrix 1.0 | Str.114.1.S1_at | Xl.3831.1.S1_at | Xl.11957.1.S1_at | ||||||||||
| Affymetrix 2.0 | Xl2.3831.1.S1_at | Xl2.11957.1.S1_at | |||||||||||
Symbol legend[+]
