Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (149) GO Terms (0) Nucleotides (299) Proteins (35) Interactants (1413) Wiki
XB-GENEPAGE-484294

Gene Symbol: sox17a

Gene Name: SRY-box 17 alpha

Synonyms: xSox17alpha1 , xSox17alpha2 , tSox17alpha , Xsox17-alpha , Sox17alpha , sox17-alpha , xsox17a , xsox17 , Xsox17alpha , sox17 alpha ( Add synonyms , Nomenclature history )

Gene Function: HMG-box transcription factor

Protein Function :
Transcription activator. Binds to the DNA sequence 5'-AACAAT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in functi...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: VESICOURETERAL REFLUX 3; VUR3

1/5
 
Xenbase Gene ID XB-GENE-484295 XB-GENE-865067 XB-GENE-6255435
Gene Symbol sox17a sox17a.L sox17a.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine sox17a sox17a.L sox17a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX17 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Sox17 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR sox17 ZFIN Ensembl
chicken
GEISHA SOX17 Ensembl
fruit fly
worm
WORMBASE
Publications
First Xsox17alpha and -beta mediate endoderm formation in Xenopus., Cell 1997    
Most Recent Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis., Stem Cells 2018                        
All View All Papers 41 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 0 term
PANTHER sox17a
KEGG Pathways K04495 K04495 K04495
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Sox17a Ab1 Sox17a Ab1 Sox17a Ab1
Morpholino sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4 sox17a MO1 , sox17a MO2 , sox17a MO3 , sox17a MO4
ORF sox17a ORF1 sox17a.L ORF1 sox17a.S ORF1
Affymetrix 1.0 Str.114.1.S1_at Xl.3831.1.S1_at Xl.11957.1.S1_at
Affymetrix 2.0 Xl2.3831.1.S1_at Xl2.11957.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.4


Major funding for Xenbase is provided by grant P41 HD064556