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Summary Expression Gene Literature (43) GO Terms (28) Nucleotides (133) Proteins (39) Interactants (258) Wiki
XB-GENEPAGE-484321
Gene Symbol:
fzd3

Gene Name:
frizzled class receptor 3

Synonyms:
Fz-3 , Xfz3 , frizzled-3 , frizzled 3 , frizzled3 , fz3 , frz3 , frz-3 ( Add synonyms , Nomenclature history )

Gene Function:
transmembrane receptor in the wnt signaling pathway

Protein Function :
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nucl...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-484322 XB-GENE-865070 XB-GENE-17343788
Gene Symbol fzd3 fzd3.L fzd3.S
Chromosome scaffold_63 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100038082
399190
108718300
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine fzd3 fzd3.L fzd3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FZD3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fzd3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fzd3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR fzd3a fzd3b ZFIN Ensembl
chicken
GEISHA FZD3 Ensembl
fruit fly
worm
Publications
First Expression of Xfz3, a Xenopus frizzled family member, is restricted to the early nervous system., Mech Dev 1998                      
Most Recent Topologically correct central projections of tetrapod inner ear afferents require Fzd3., Sci Rep 2019                
All View All Papers 9 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 23 terms 8 terms 3 terms
PANTHER fzd3
KEGG Pathways K02329 [+] K02329 K02329
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fzd3
Morpholinos fzd3 MO1 fzd3 MO1 fzd3 MO1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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Version: 4.14.0
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