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Summary Expression Gene Literature (34) GO Terms (7) Nucleotides (51) Proteins (21) Interactants (253) Wiki
XB-GENEPAGE-484424

Gene Symbol: ptf1a

Gene Name: pancreas associated transcription factor 1a

Synonyms: Ptf1a/p48 , XPtf1a , ptf1a-a , ptf1a-b ( Add synonyms , Nomenclature history )

Gene Function: transcription factor

Protein Function :
Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Acts together with pdx1 to induce the pancreatic lineage within the...[+]

Interactants: Loading ...
Disease Ontology:

OMIM Diseases: PANCREATIC AND CEREBELLAR AGENESIS; PACA [+]

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Xenbase Gene ID XB-GENE-484425 XB-GENE-6466546 XB-GENE-484429
Gene Symbol ptf1a ptf1a.L ptf1a.S
Chromosome Chr06 Scaffold155082
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine ptf1a ptf1a.L ptf1a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PTF1A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ptf1a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ptf1a ZFIN Ensembl
chicken
GEISHA PTF1A Ensembl
fruit fly
worm
WORMBASE
Publications
First The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification., Dev Biol 2006                        
Most Recent CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Drug Discov Today Technol 2018  
All View All Papers 12 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 0 term
PANTHER ptf1a
KEGG Pathways K09073
KOG [K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
Dharmacon Dharmacon Dharmacon
Morpholino ptf1a MO1 , ptf1a MO2 , ptf1a MO3 ptf1a MO1 , ptf1a MO2 , ptf1a MO3 ptf1a MO1 , ptf1a MO2 , ptf1a MO3
Affymetrix 1.0 Str.36339.1.S1_at
Affymetrix 2.0 Xl2.29862.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.4


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