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XB-GENEPAGE-484424
Gene Symbol:
ptf1a
Gene Name: pancreas associated transcription factor 1a
Synonyms:
Ptf1a/p48
,
XPtf1a
,
ptf1a-a
,
ptf1a-b
( Gene Function: transcription factor Protein Function
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Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Acts together with pdx1 to induce the pancreatic lineage within the...[+]
Interactants:
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Diseases: Disease Ontology:
pancreatic agenesis
OMIM:
PANCREATIC AND CEREBELLAR AGENESIS; PACA
External Links:
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Xenbase Gene ID
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XB-GENE-484425 | XB-GENE-6466546 | XB-GENE-484429 | |||||
Gene Symbol | ptf1a | ptf1a.L | ptf1a.S | Chromosome | Chr6 | chr6L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.2
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CDS |
Gene model
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Gene model
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Entrez Gene |
100494161
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100381084
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | ptf1a | ptf1a.L | ptf1a.S | |||||
Orthology ![]() |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification., Dev Biol 2006 ![]() |
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Most Recent |
CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Drug Discov Today Technol 2018 |
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All | View All Papers 12 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 13 terms | 12 terms | 0 term | |||||
PANTHER | ptf1a | |||||||
KEGG Pathways | K09073 | K09073 | ||||||
KOG |
[K] Transcription factor HAND2/Transcription factor TAL1/TAL2/LYL1
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | ptf1a | |||||||
Morpholinos | ptf1a MO2 , ptf1a MO3 | |||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



