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Summary Expression Gene Literature (272) Nucleotides (515) Proteins (32) Interactants (910) Wiki
XB-GENEPAGE-484552

Gene Symbol: sox2

Gene Name: SRY (sex determining region Y)-box 2

Synonyms: XLSOX-2, Sox-2, XSox2, Xsox-2, anop3, mcops3 Add Xenopus synonyms

Gene Function: HMG-box transcription factor

Interactants: chrd(83) , snai2(75) , t(75) , otx2(72) , tubb2b(66) , nog(61) , bmp4(57) View All

Disease Associations: MICROPHTHALMIA, SYNDROMIC 3; MCOPS3
1/5
 
  XB-GENE-484553 XB-GENE-865099
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 Ensembl 4.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v6.0 gene model
Links
tropicalis 4.1 synteny
Expression tropicalis laevis
UniGene Str.6201 [+] Xl.188
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 308 expression image(s) for tropicalis and laevis
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC SOX2 OMIM:206900
mouse
MGI Sox2 All
zebrafish
ZFIN sox2
chicken
GEISHA SOX2
Publications
First: Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. [Development 1997]
Most recent: Sp8 regulates inner ear development. [Proc Natl Acad Sci U S A 2014]
View All Papers 114 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
      Biological: regulation of transcription, DNA-dependent
      Cellular Component:
EC:
KOG: [K] HMG-box transcription factor
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Sox2 Ab1, Sox2 Ab2, Sox2 Ab3 Sox2 Ab1, Sox2 Ab3
Morpholino sox2 MO1, sox2 MO2, sox2 MO3, sox2 MO4 sox2 MO1, sox2 MO2, sox2 MO3, sox2 MO4
Affymetrix 1.0 Str.43967.1.A1_at [+] Xl.188.1.S1_at [+]
Affymetrix 2.0 Xl2.188.1.S1_a_at [+]

Symbol legend[+]

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