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Summary Expression Gene Literature (348) Nucleotides (515) Proteins (32) Interactants (1269) Wiki
XB-GENEPAGE- 484552

Gene Symbol: sox2

Gene Name: SRY-box 2

Synonyms: XLSOX-2 , Sox-2 , XSox2 , Xsox-2 , anop3 , mcops3
Add Xenopus synonyms , Nomenclature history


Gene Function: HMG-box transcription factor

Interactants: chrd.1 (99) , t (97) , snai2 (93) , otx2 (88) , myc (79) , bmp4 (75) , tubb2b (75) View All

OMIM Disease Associations: MICROPHTHALMIA, SYNDROMIC 3; MCOPS3
1/6
 
Xenbase Gene ID XB-GENE-484553 XB-GENE-17341038 XB-GENE-865099
Gene Symbol sox2 sox2.L sox2.S
Chromosome: Chr05 Scaffold33547
Molecules tropicalis laevis .L laevis.S
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis laevis .L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis .L laevis.S
Ensembl Ensembl
UniGene Str.6201 [+] Xl.188
RNA-seq profile: Owens, Blitz et al. 2016 sox2
Images 351 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis .L laevis.S
XenMine sox2 sox2.L sox2.S
Phenotype tropicalis laevis .L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Sox2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN sox2 ZFIN Ensembl
chicken
GEISHA SOX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Neural crest formation in Xenopus laevis: mechanisms of Xslug induction. [Dev Biol 1996]
Most recent: Autoregulation of retinal homeobox (rax) gene promoter activity through a highly conserved genomic element. [Genesis 2016]
View All Papers 138 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding  
      Biological: regulation of transcription, DNA-templated  
      Cellular Component:
EC:
PANTHER: sox2
KOG: [K] HMG-box transcription factor
Reagents tropicalis laevis .L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)   EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Sox2 Ab1 , Sox2 Ab2 , Sox2 Ab3 , Sox2 Ab5 Sox2 Ab5 , Sox2 Ab1 Sox2 Ab1 , Sox2 Ab3 , Sox2 Ab5
Morpholino sox2 MO1 , sox2 MO2 , sox2 MO3 , sox2 MO4 , sox2 MO5 sox2 MO1 , sox2 MO2 , sox2 MO3 , sox2 MO4 , sox2 MO5 sox2 MO1 , sox2 MO2 , sox2 MO3 , sox2 MO4 , sox2 MO5
Affymetrix 1.0 Str.43967.1.A1_at [+] Xl.188.1.S1_at [+]
Affymetrix 2.0 Xl2.188.1.S1_a_at [+]

Symbol legend[+]

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