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XB-GENEPAGE-484552
Gene Symbol:
sox2
Gene Name: SRY-box 2
Synonyms:
XLSOX-2
,
Sox-2
,
XSox2
,
Xsox-2
,
anop3
,
mcops3
( Gene Function: HMG-box transcription factor Protein Function
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Transcriptional activator. Functions as a switch in neuronal development, participating in the differentiation of embryonic neuroectodermal cells into neural tissues by making the ectodermal cells resp...[+]
Interactants:
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Diseases: Disease Ontology:
septooptic dysplasia
OMIM:
MICROPHTHALMIA, SYNDROMIC 3; MCOPS3
External Links:
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Xenbase Gene ID | XB-GENE-484553 | XB-GENE-865099 | XB-GENE-17341038 | |||||
Gene Symbol | sox2 | sox2.L | sox2.S | Chromosome | Chr5 | chr5L | chr5S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.2
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CDS |
Gene model
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Gene model
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Entrez Gene |
407873
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398000
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | sox2 | sox2.L | sox2.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Neural crest formation in Xenopus laevis: mechanisms of Xslug induction., Dev Biol 1996 ![]() |
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Most Recent |
Retinoic acid production, regulation, and containment through Zic1, Pitx2c and Cyp26c1 control cranial placode specification., Development 2021 |
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All | View All Papers 145 paper(s) referencing morpholinos 16 paper(s) referencing OMIMs 23 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 29 terms | 8 terms | 0 term | |||||
PANTHER | sox2 | |||||||
KEGG Pathways | K16796 | K16796 | ||||||
KOG |
[K] HMG-box transcription factor
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | sox2 | |||||||
Antibodies | Sox2 Ab5 , Sox2 Ab1 , Sox2 Ab2 , Sox2 Ab3 , Sox2 Ab6 , Sox2 Ab7 , sox2 Ab8 | Sox2 Ab5 , Sox2 Ab1 , Sox2 Ab3 , Sox2 Ab6 , Sox2 Ab7 , sox2 Ab8 | Sox2 Ab5 , Sox2 Ab1 , Sox2 Ab3 , Sox2 Ab6 , Sox2 Ab7 , sox2 Ab8 | |||||
Morpholinos (on-target & off-target) | sox2 MO1 , sox2 MO3 , sox2 MO2 | |||||||
ORFs | sox2 ORF1 | |||||||
Clones | EXRC Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
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