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Summary Expression Gene Literature (112) GO Terms (34) Nucleotides (553) Proteins (44) Interactants (435) Wiki
XB-GENEPAGE-484610
Gene Symbol:
amd1

Gene Name:
adenosylmethionine decarboxylase 1

Synonyms:
mgc53431 , AdoMetDC , S-adenosylmethionine decarboxylase , samdc ( Add synonyms , Nomenclature history )

Gene Function:
polyamine biosynthetic enzyme

Protein Function :
Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-484611 XB-GENE-484615 XB-GENE-17346705
Gene Symbol amd1 amd1.L amd1.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549897
380052
108717936
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine amd1 amd1.L amd1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards AMD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Amd1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Amd1 Ensembl
zebrafish
ZFIN, AGR amd1 ZFIN Ensembl
chicken
GEISHA AMD1 Ensembl
fruit fly
worm
Publications
First Down-regulation of ornithine decarboxylase by an increased degradation of the enzyme during gastrulation of Xenopus laevis., Biochim Biophys Acta 1995  
Most Recent Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Int J Dev Biol 2014                  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 34 terms 4 terms 4 terms
PANTHER amd1
KEGG Pathways K01611 K01611 K01611
KOG [T] S-adenosylmethionine decarboxylase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks amd1
ORFs amd1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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