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Summary Expression Gene Literature (3) GO Terms (9) Nucleotides (45) Proteins (23) Interactants (97) Wiki
Gene Symbol:

Gene Name:
insulin like growth factor binding protein 4

XIGFBP-4 , XBP4 ( Add synonyms , Nomenclature history )

Gene Function:
growth factor binding

Protein Function :
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs wi...[+]

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External Links:
Xenbase Gene ID XB-GENE-484795 XB-GENE-6486695 XB-GENE-17330677
Gene Symbol igfbp4 igfbp4.L igfbp4.S
Chromosome scaffold_39 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100498651
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein TrEMBL NCBI Protein TrEMBL
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine igfbp4 igfbp4.L igfbp4.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards IGFBP4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Igfbp4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Igfbp4 Ensembl
fruit fly
First IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis., Nature 2008                          
Most Recent Characterization of the insulin-like growth factor binding protein family in Xenopus tropicalis., Int J Dev Biol 2014                                              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 3 terms 3 terms
PANTHER igfbp4
KEGG Pathways K23576 K23576
KOG [T] Fibrillins and related proteins containing Ca2+-binding EGF-like domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks igfbp4
Morpholinos Igfbp4 MO1 , Igfbp4 MO2 Igfbp4 MO1 , Igfbp4 MO2 Igfbp4 MO1 , Igfbp4 MO2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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