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Summary Expression Gene Literature (200) GO Terms (20) Nucleotides (567) Proteins (30) Interactants (1414) Wiki
XB-GENEPAGE- 484814

Gene Symbol: sox3

Gene Name: SRY-box 3

Synonyms: xSox3 , Sry , Xtsox3 , Xlsox3
Add Xenopus synonyms , Nomenclature history


Gene Function: HMG-box transcription factor

Protein Function :
Transcription factor with sequence-specific DNA binding activity. Binds to the consensus sequence 5'-[AT][AT]CAA[AT]G-3', showing a preference for 5'-AACAAT-3' and 5'-AACAAAG-3'. Inhibits beta-catenin-...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
   MENTAL RETARDATION, X-LINKED, WITH PANHYPOPITUITARISM [+]
1/7
 

Xenbase Gene ID XB-GENE-484815 XB-GENE-17345032 XB-GENE-484819
Gene Symbol sox3 sox3.L sox3.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.27268 [+] Xl.22
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 193 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine sox3 sox3.L sox3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SOX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Sox3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR sox3 ZFIN Ensembl
chicken
GEISHA SOX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Blastoderm-specific and read-through transcription of the sry alpha gene transformed into the Drosophila genome. [Dev Biol 1986]
Most recent: Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads. [Differentiation 9999]
View All Papers 60 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 7 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 0 term 15 terms
PANTHER sox3
KEGG Pathways K09267 K09267
KOG [K] HMG-box transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Sox3 Ab1 , Sox3 Ab2 Sox3 Ab1 , Sox3 Ab2
Morpholino sox3 MO1 , sox3 MO2 , sox3 MO3 , sox3 MO4 sox3 MO1 , sox3 MO2 , sox3 MO3 , sox3 MO4 sox3 MO1 , sox3 MO2 , sox3 MO3 , sox3 MO4
ORF sox3 ORF1 , sox3 ORF1 sox3.S ORF1
Affymetrix 1.0 Str.27268.1.S1_at [+] Xl.22.1.S1_at
Affymetrix 2.0 Xl2.22.1.S1_at

Symbol legend[+]
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