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Summary Expression Gene Literature (154) GO Terms (17) Nucleotides (1808) Proteins (60) Interactants (600) Wiki
XB-GENEPAGE-484830
Gene Symbol:
atp1a1

Gene Name:
ATPase Na+/K+ transporting subunit alpha 1

Synonyms:
Na+/K+ ATPase , Na+K+ ATPase , Na+K+ATPase , K-ATPase , atp1a1-a , atp1a1-b ( Add synonyms , Nomenclature history )

Gene Function:
cation transporting ATPase subunit

Protein Function :
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the el...[+]


InterPro :
Apc13 , CRAL-TRIO dom , ATPase P-typ TM dom sf , HAD-like sf [+]

Interactants:
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Diseases: 


Disease Ontology:
Charcot-Marie-Tooth disease type 2DD

OMIM:
CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2DD; CMT2DD

External Links:
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Xenbase Gene ID XB-GENE-484831 XB-GENE-6254180 XB-GENE-865506
Gene Symbol atp1a1 atp1a1.L atp1a1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 395044
399285
398583
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine atp1a1 atp1a1.L atp1a1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ATP1A1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Atp1a1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Atp1a1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR atp1a1a.1 atp1a1b ZFIN Ensembl
chicken
GEISHA ATP1A1 Ensembl
fruit fly
worm
Publications
First Na,K-ATPase from Xenopus laevis kidney and epidermis: ouabain interaction studies., Boll Soc Ital Biol Sper 1982  
Most Recent Nucleoporin NUP205 plays a critical role in cilia and congenital disease., Dev Biol 2021                          
All View All Papers 5 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 14 terms 5 terms
PANTHER atp1a1
KEGG Pathways K01539 K01539 K01539
KOG [P] Na+/K+ ATPase, alpha subunit
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks atp1a1
Antibodies Atp1a1 Ab1 , Atp1a1 Ab2 , Atp1a1 Ab3 , Atp1a1 Ab4 Atp1a1 Ab1 , Atp1a1 Ab3 , Atp1a1 Ab4 Atp1a1 Ab1 , Atp1a1 Ab3 , Atp1a1 Ab4
ORFs atp1a1.L ORF1 , atp1a1.L ORF2 atp1a1.S ORF1 , atp1a1.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info